HitPredict

Interactor 1: EIF3B (P55884)
Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Eukaryotic translation initiation factor 3 subunit 9) (Prt1 homolog) (hPrt1) (eIF-3-eta) (eIF3 p110) (eIF3 p116)
Gene: EIF3B

Interactor 2: G3BP1 (Q13283)
Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent DNA helicase VIII) (hDH VIII) (GAP SH3 domain-binding protein 1)
Gene: G3BP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	26777405, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol GO:0010494 - cytoplasmic stress granule
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 814 Hs			1 466
+	Hs
		879363 EIF3B_HUMAN (1-814): 0: 830: 100.00		G3BP2_HUMAN (1-463): 4.59e-76: 248: 58.68
+	Hs
		1030466 EIF2A_HUMAN (329-769): 3.23e-74: 255: 19.50		G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00
+	Sc
		410155 EIF3B_YEAST (139-790): 1.9e-118: 377: 29.36		BRE5_YEAST (9-441): 5.6e-45: 166: 15.31
+	Sc
		860334 EIF2A_YEAST (343-705): 1.57e-86: 289: 19.95		BRE5_YEAST (9-441): 5.6e-45: 166: 15.31
+	Hs
		903195 WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71		G3BP1_HUMAN (1-466): 1.13e-102: 316: 100.00
+	Hs
		903606 WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71		G3BP2_HUMAN (1-463): 4.59e-76: 248: 58.68