Protein: NR2C1
Nuclear receptor subfamily 2 group C member 1 (Orphan nuclear receptor TR2) (Testicular receptor 2)

Gene: NR2C1
Organism: Homo sapiens
Interactions: 83
UniProt ID: P13056

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

559739

NR2C2
Nuclear receptor subfamily 2 group C member 2

2

16

Small-scale

0.789

High

520504

RARA
Retinoic acid receptor alpha

2

17

High-throughput

0.783

High

395403

ESR1
Estrogen receptor

1

20

Small-scale

0.747

High

188161

HDAC3
Histone deacetylase 3

5

20

Small-scale

0.730

High

519702

ANDR
Androgen receptor

1

20

Small-scale

0.713

High

559745

HDAC4
Histone deacetylase 4

2

20

Small-scale

0.629

High

559735

HNF4A
Hepatocyte nuclear factor 4-alpha

1

20

High-throughput

0.618

High

142806

NFIB
Nuclear factor 1 B-type

2

20

High-throughput

0.584

High

473755

NFIC
Nuclear factor 1 C-type

2

20

High-throughput

0.584

High

559729

PML
Protein PML

2

20

Small-scale

0.584

High

559737

SOX2
Transcription factor SOX-2

2

20

Small-scale

0.584

High

559746

KLF3
Krueppel-like factor 3

2

20

High-throughput

0.584

High

559752

NFIA
Nuclear factor 1 A-type

2

20

High-throughput

0.584

High

559762

NFIX
Nuclear factor 1 X-type

2

20

High-throughput

0.584

High

559738

NRIP1
Nuclear receptor-interacting protein 1

1

13

High-throughput

0.541

High

559769

JAZF1
Juxtaposed with another zinc finger protein 1

1

3

High-throughput

0.536

High

352672

NUDT3
Diphosphoinositol polyphosphate phosphohydrolase 1

1

1

High-throughput

0.508

High

181486

TBXT
T-box transcription factor T

1

7

High-throughput

0.479

High

209946

CRX
Cone-rod homeobox protein

1

20

High-throughput

0.479

High

224932

TLX3
T-cell leukemia homeobox protein 3

1

20

High-throughput

0.479

High

226510

TLX2
T-cell leukemia homeobox protein 2

1

20

High-throughput

0.479

High

239917

SOX15
Transcription factor SOX-15

1

20

High-throughput

0.479

High

246415

KDM1A
Lysine-specific histone demethylase 1A

1

13

Small-scale

0.479

High

316738

MTA2
Metastasis-associated protein MTA2

1

11

Small-scale

0.479

High

339640

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.479

High

352062

MBD3
Methyl-CpG-binding domain protein 3

1

9

Small-scale

0.479

High

371045

MYC
Myc proto-oncogene protein

1

13

High-throughput

0.479

High

486905

PARP1
Poly [ADP-ribose] polymerase 1

1

5

High-throughput

0.479

High

519324

MYB
Transcriptional activator Myb

1

5

High-throughput

0.479

High

538363

EGR2
E3 SUMO-protein ligase EGR2

1

8

High-throughput

0.479

High

559722

MYOD1
Myoblast determination protein 1

1

12

High-throughput

0.479

High

559723

SFPQ
Splicing factor, proline- and glutamine-rich

1

15

Small-scale

0.479

High

559724

PAX7
Paired box protein Pax-7

1

20

High-throughput

0.479

High

559725

DNMT1
DNA

1

11

Small-scale

0.479

High

559726

PAX6
Paired box protein Pax-6

1

20

High-throughput

0.479

High

559728

TEAD1
Transcriptional enhancer factor TEF-1

1

2

High-throughput

0.479

High

559730

TLX1
T-cell leukemia homeobox protein 1

1

20

High-throughput

0.479

High

559731

ELF1
ETS-related transcription factor Elf-1

1

13

High-throughput

0.479

High

559732

HNF1B
Hepatocyte nuclear factor 1-beta

1

20

High-throughput

0.479

High

559733

SOX6
Transcription factor SOX-6

1

20

High-throughput

0.479

High

559734

ETV3
ETS translocation variant 3

1

12

High-throughput

0.479

High

559736

ELK3
ETS domain-containing protein Elk-3

1

13

High-throughput

0.479

High

559740

CEBPA
CCAAT/enhancer-binding protein alpha

1

15

High-throughput

0.479

High

559741

LHX2
LIM/homeobox protein Lhx2

1

16

High-throughput

0.479

High

559742

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

20

Small-scale

0.479

High

559743

HCFC1
Host cell factor 1

1

3

Small-scale

0.479

High

559744

PAX9
Paired box protein Pax-9

1

20

High-throughput

0.479

High

559747

FOXL2
Forkhead box protein L2

1

20

Small-scale

0.479

High

559748

H31
Histone H3.1

1

5

High-throughput

0.479

High

559749

H33
Histone H3.3

1

5

High-throughput

0.479

High

559751

RBBP4
Histone-binding protein RBBP4

1

13

Small-scale

0.479

High

559753

TP53B
TP53-binding protein 1

1

2

High-throughput

0.479

High

559754

TIF1B
Transcription intermediary factor 1-beta

1

20

Small-scale

0.479

High

559755

MTA1
Metastasis-associated protein MTA1

1

11

Small-scale

0.479

High

559756

HDAC1
Histone deacetylase 1

1

20

Small-scale

0.479

High

559757

KLF9
Krueppel-like factor 9

1

20

High-throughput

0.479

High

559758

KLF5
Krueppel-like factor 5

1

20

High-throughput

0.479

High

559759

NFYC
Nuclear transcription factor Y subunit gamma

1

4

High-throughput

0.479

High

559760

RBM39
RNA-binding protein 39

1

10

Small-scale

0.479

High

559761

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

14

Small-scale

0.479

High

559763

DPOD3
DNA polymerase delta subunit 3

1

1

Small-scale

0.479

High

559764

NONO
Non-POU domain-containing octamer-binding protein

1

18

Small-scale

0.479

High

559765

ELF2
ETS-related transcription factor Elf-2

1

11

High-throughput

0.479

High

559766

RBBP7
Histone-binding protein RBBP7

1

14

Small-scale

0.479

High

559768

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

559770

SMC5
Structural maintenance of chromosomes protein 5

1

7

High-throughput

0.479

High

559771

NUP43
Nucleoporin Nup43

1

17

High-throughput

0.479

High

559772

PSPC1
Paraspeckle component 1

1

18

Small-scale

0.479

High

559773

HDAC2
Histone deacetylase 2

1

20

Small-scale

0.479

High

559774

LHX4
LIM/homeobox protein Lhx4

1

15

High-throughput

0.479

High

559775

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

8

High-throughput

0.479

High

559776

SIN3A
Paired amphipathic helix protein Sin3a

1

2

Small-scale

0.479

High

559777

FEV
Protein FEV

1

12

High-throughput

0.479

High

559778

KLF16
Krueppel-like factor 16

1

20

High-throughput

0.479

High

559780

VSX1
Visual system homeobox 1

1

20

High-throughput

0.479

High

559781

LHX3
LIM/homeobox protein Lhx3

1

13

High-throughput

0.479

High

559782

RCOR1
REST corepressor 1

1

20

Small-scale

0.479

High

559783

KLF12
Krueppel-like factor 12

1

20

High-throughput

0.479

High

559784

ETV7
Transcription factor ETV7

1

13

High-throughput

0.479

High

559727

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

559750

NDP
Norrin

1

0

Small-scale

0.458

High

559779

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

559767

FBX38
F-box only protein 38

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025