HitPredict

Interactor 1: EIF3B (P55884)
Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Eukaryotic translation initiation factor 3 subunit 9) (Prt1 homolog) (hPrt1) (eIF-3-eta) (eIF3 p110) (eIF3 p116)
Gene: EIF3B

Interactor 2: A16L1 (Q676U5)
Autophagy-related protein 16-1 (APG16-like 1)
Gene: ATG16L1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30196744
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	eIF2A~WD40
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 814 Hs			1 607
+	Hs
		879196 EIF3B_HUMAN (1-814): 0: 830: 100.00		WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45
+	Mm
		1207605 EIF3B_MOUSE (1-814): 0: 764: 90.69		A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25
+	Hs
		1146810 EIF2A_HUMAN (329-769): 3.23e-74: 255: 19.50		A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00
+	Hs
		1074793 TAF5_HUMAN (304-497): 3.2e-13: 75.6: 18.32		A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00
+	Dm
		1358845 WDS_DROME (553-729): 2.22e-33: 134: 12.09		WDS_DROME (279-565): 1.49e-87: 278: 18.27
+	Sc
		630844 NLE1_YEAST (419-730): 1.18e-55: 201: 11.69		NLE1_YEAST (42-474): 1.95e-50: 184: 12.40
+	Sp
		999842 TUP12_SCHPO (233-498): 5.52e-30: 128: 17.73		TUP11_SCHPO (6-518): 9.92e-73: 246: 12.61
+	Mm
		1206766 EIF2A_MOUSE (323-743): 1.19e-74: 255: 20.73		A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25
+	Hs
		903428 WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71		SNR40_HUMAN (175-514): 5.61e-65: 218: 16.48
+	Hs
		792949 WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71		LIS1_HUMAN (99-438): 6.8e-50: 180: 14.98
+	Hs
		1346954 NLE1_HUMAN (507-723): 2.49e-34: 139: 17.03		NLE1_HUMAN (441-607): 2.75e-43: 163: 20.34
+	Hs
		921751 NLE1_HUMAN (507-723): 2.49e-34: 139: 17.03		GBB2_HUMAN (165-516): 9.92e-44: 161: 16.62
+	Hs
		792935 LIS1_HUMAN (231-410): 5.42e-23: 104: 10.73		LIS1_HUMAN (99-438): 6.8e-50: 180: 14.98
+	Mm
		925836 LIS1_MOUSE (231-410): 4.81e-23: 104: 10.73		LIS1_MOUSE (99-438): 1.81e-49: 179: 14.98
+	Hs
		903551 NLE1_HUMAN (507-723): 2.49e-34: 139: 17.03		WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45
+	Hs
		903349 WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71		WDR5B_HUMAN (165-393): 1.21e-20: 95.1: 11.72
+	Hs
		903077 WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71		WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45
+	Sc
		744605 TAF5_YEAST (304-498): 7.47e-13: 74.5: 19.61		TAF5_YEAST (129-424): 1.16e-19: 95.5: 9.33