Interactor 1: BID (P55957)
BH3-interacting domain death agonist (p22 BID) (BID) [Cleaved into: BH3-interacting domain death agonist p15 (p15 BID); BH3-interacting domain death agonist p13 (p13 BID); BH3-interacting domain death agonist p11 (p11 BID)]
Gene: BID
Interactor 2: B2CL1 (Q07817)
Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)
Gene: BCL2L1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.971 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15721256, 16697956, 15694340, 33961781, 27159560, 24814347, 14963330, 19074440, 17289999 |
| Identification Methods | unspecified method, affinity chromatography technology, fluorescence polarization spectroscopy, isothermal titration calorimetry, anti tag coimmunoprecipitation, pull down, surface plasmon resonance |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | BID~Bcl-2 |
| Common GO terms | GO:0001836 - release of cytochrome c from mitochondria GO:0005739 - mitochondrion GO:0005741 - mitochondrial outer membrane GO:0005829 - cytosol GO:0008637 - apoptotic mitochondrial changes and 3 others more... |
| Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
