HitPredict

Interactor 1: TPTE (P56180)
Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Cancer/testis antigen 44) (CT44) (Transmembrane phosphatase with tensin homology) (Tumor antigen BJ-HCC-5)
Gene: TPTE

Interactor 2: PHB2 (Q99623)
Prohibitin-2 (B-cell receptor-associated protein BAP37) (D-prohibitin) (Repressor of estrogen receptor activity)
Gene: PHB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	27432908, 28330616
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 551 Hs			1 299
+	Hs
		718663 TPTE_HUMAN (1-551): 0: 759: 100.00		PHB1_HUMAN (22-280): 1e-85: 259: 51.15
+	Mm
		139285 PTEN_MOUSE (215-550): 1.45e-106: 327: 32.44		PHB2_MOUSE (1-299): 2.46e-109: 320: 100.00
+	Hs
		890817 PTEN_HUMAN (215-550): 1.26e-106: 327: 32.44		PHB2_HUMAN (1-299): 2.46e-109: 320: 100.00
+	Mm
		139364 PTEN_MOUSE (215-550): 1.45e-106: 327: 32.44		PHB1_MOUSE (22-280): 6.64e-86: 260: 51.54
+	Hs
		718669 PTEN_HUMAN (215-550): 1.26e-106: 327: 32.44		PHB1_HUMAN (22-280): 1e-85: 259: 51.15