Interactor 1: SYMC (P56192)
Methionine--tRNA ligase, cytoplasmic (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)
Gene: MARS1

Interactor 2: SYK (Q15046)
Lysine--tRNA ligase (EC 2.7.7.-) (EC 6.1.1.6) (Lysyl-tRNA synthetase) (LysRS)
Gene: KARS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.628

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000049 - tRNA binding
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0017101 - aminoacyl-tRNA synthetase multienzyme complex
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 900
Hs

1 597
+ Ce
+ Sc
+ Dm
+ Sc
+ Sc
+ Hs
+ Sc
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024