Protein: AL1A1
Aldehyde dehydrogenase 1A1 (EC 1.2.1.19) (EC 1.2.1.28) (EC 1.2.1.3) (EC 1.2.1.36) (3-deoxyglucosone dehydrogenase) (ALDH-E1) (ALHDII) (Aldehyde dehydrogenase family 1 member A1) (Aldehyde dehydrogenase, cytosolic) (Retinal dehydrogenase 1) (RALDH 1) (RalDH1)

Gene: AL1A1, ALDH1A1
Organism: Homo sapiens
Interactions: 59
UniProt ID: P00352

Gene Ontology (top 5):
GO:0001523 - retinoid metabolic process
GO:0001758 - retinal dehydrogenase (NAD+) activity
GO:0004029 - aldehyde dehydrogenase (NAD+) activity
GO:0005096 - GTPase activator activity
GO:0005497 - androgen binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

358863

AL1A1
Aldehyde dehydrogenase 1A1

2

14

High-throughput

0.815

High

358865

ALDH2
Aldehyde dehydrogenase, mitochondrial

2

15

High-throughput

0.793

High

317231

AL1A2
Retinal dehydrogenase 2

1

14

High-throughput

0.665

High

358870

GTR3
Solute carrier family 2, facilitated glucose transporter member 3

1

5

High-throughput

0.536

High

358882

CYC
Cytochrome c

1

1

High-throughput

0.536

High

358896

BAG1
BAG family molecular chaperone regulator 1

1

1

High-throughput

0.536

High

247587

NUPR1
Nuclear protein 1

1

0

High-throughput

0.518

High

358871

GFAP
Glial fibrillary acidic protein

1

1

High-throughput

0.515

High

132546

UPK1A
Uroplakin-1a

1

0

High-throughput

0.513

High

135864

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

0

High-throughput

0.513

High

187237

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

0

High-throughput

0.513

High

358867

FGF4
Fibroblast growth factor 4

1

0

High-throughput

0.513

High

358886

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

0

High-throughput

0.513

High

358908

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.513

High

358872

CHIN
N-chimaerin

1

0

High-throughput

0.493

High

358895

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

1

0

High-throughput

0.493

High

358897

P4K2A
Phosphatidylinositol 4-kinase type 2-alpha

1

0

High-throughput

0.493

High

358868

DOPO
Dopamine beta-hydroxylase

1

0

High-throughput

0.493

High

325248

OR2A4
Olfactory receptor 2A4

1

3

High-throughput

0.489

High

358877

PTSS1
Phosphatidylserine synthase 1

1

1

High-throughput

0.489

High

358880

DSCR6
Protein ripply3

1

1

High-throughput

0.489

High

358889

FNDC5
Fibronectin type III domain-containing protein 5

1

2

High-throughput

0.489

High

358890

O13C3
Olfactory receptor 13C3

1

1

High-throughput

0.489

High

358891

ZDH19
Palmitoyltransferase ZDHHC19

1

1

High-throughput

0.489

High

358907

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

1

High-throughput

0.489

High

131267

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

1

Small-scale

0.479

High

358866

ISG15
Ubiquitin-like protein ISG15

1

5

High-throughput

0.479

High

358875

CTNB1
Catenin beta-1

1

1

Small-scale

0.479

High

358879

TERA
Transitional endoplasmic reticulum ATPase

1

5

High-throughput

0.479

High

358881

1433Z
14-3-3 protein zeta/delta

1

1

High-throughput

0.479

High

358888

TIAM2
Rho guanine nucleotide exchange factor TIAM2

1

1

High-throughput

0.479

High

358901

ACE2
Angiotensin-converting enzyme 2

1

1

Small-scale

0.479

High

358902

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.479

High

358906

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

358864

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

0

High-throughput

0.458

High

358873

RO52
E3 ubiquitin-protein ligase TRIM21

1

0

High-throughput

0.458

High

358876

NOS2
Nitric oxide synthase, inducible

1

0

High-throughput

0.458

High

358869

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.445

High

105046

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

332066

MRP6
ATP-binding cassette sub-family C member 6

1

1

Small-scale

0.437

High

352812

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

358878

CDK9
Cyclin-dependent kinase 9

1

2

High-throughput

0.437

High

261035

NSMA
Sphingomyelin phosphodiesterase 2

1

2

High-throughput

0.407

High

358905

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.282

High

340716

CPSF4
Cleavage and polyadenylation specificity factor subunit 4

1

0

High-throughput

0.279

Low

358885

CR021
UPF0711 protein C18orf21

1

0

High-throughput

0.279

Low

358892

ITLN2
Intelectin-2

1

0

High-throughput

0.279

Low

358894

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

358898

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.279

Low

358899

ALG8
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase

1

0

High-throughput

0.279

Low

358900

FUND2
FUN14 domain-containing protein 2

1

0

High-throughput

0.279

Low

358903

COE2
Transcription factor COE2

1

0

High-throughput

0.279

Low

358904

IL21
Interleukin-21

1

0

High-throughput

0.269

Low

358893

JPH3
Junctophilin-3

1

0

High-throughput

0.268

Low

358874

TCEA1
Transcription elongation factor A protein 1

1

0

High-throughput

0.249

Low

358883

IL5RA
Interleukin-5 receptor subunit alpha

1

0

High-throughput

0.232

Low

358884

NONO
Non-POU domain-containing octamer-binding protein

1

0

High-throughput

0.232

Low

358887

ZC3C1
Zinc finger C3HC-type protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025