Interactor 1: HDAC4 (P56524)
Histone deacetylase 4 (HD4) (EC 3.5.1.98)
Gene: HDAC4

Interactor 2: HDAC9 (Q9UKV0)
Histone deacetylase 9 (HD9) (EC 3.5.1.98) (Histone deacetylase 7B) (HD7) (HD7b) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR)
Gene: HDAC9

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.46 1.00 0.681

The method score is based on:

Property Details
Experiments 12590135
Identification Methods pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HDAC4_Gln~HDAC4_Gln, Hist_deacetyl~Hist_deacetyl
Common GO terms GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0004407 - histone deacetylase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 10 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1084
Hs

1 1011
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Last updated: 15 Jul 2024