HitPredict

Interactor 1: IF6 (P56537)
Eukaryotic translation initiation factor 6 (eIF-6) (B(2)GCN homolog) (B4 integrin interactor) (CAB) (p27(BBP))
Gene: EIF6

Interactor 2: BRX1 (Q8TDN6)
Ribosome biogenesis protein BRX1 homolog (Brix domain-containing protein 2)
Gene: BRIX1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 353
+	Sc
		994476 IF6_YEAST (1-245): 2.46e-139: 392: 72.25		BRX1_YEAST (40-305): 1.92e-92: 279: 45.32
+	Sc
		755355 IF6_YEAST (1-245): 2.46e-139: 392: 72.25		RPF1_YEAST (4-269): 5.6e-62: 201: 15.33
+	Hs
		881033 IF6_HUMAN (1-245): 5.45e-148: 414: 100.00		SSF1_HUMAN (54-228): 2.87e-21: 96.4: 15.22
+	Sc
		754942 IF6_YEAST (1-245): 2.46e-139: 392: 72.25		SSF1_YEAST (39-230): 7.36e-18: 86.4: 14.88
+	Sc
		733992 IF6_YEAST (1-245): 2.46e-139: 392: 72.25		RPF2_YEAST (71-267): 1.62e-13: 72.5: 19.56