HitPredict

Interactor 1: BCAR1 (P56945)
Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas)
Gene: BCAR1

Interactor 2: SPTN1 (Q13813)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)
Gene: SPTAN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	28007913
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	SH3_1~SH3_1
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 870 Hs			1 2472
+	Hs
		882242 BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00		SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52
+	Hs
		166686 BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00		CE290_HUMAN (808-2443): 1.12e-32: 142: 10.61
+	Hs
		882642 BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00		MACF1_HUMAN (9-1261): 9.1e-18: 93.6: 12.48
+	Hs
		521513 BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00		ACTN1_HUMAN (1862-2210): 3.16e-11: 71.2: 22.25
+	Hs
		1068700 MACF1_HUMAN (505-867): 1.44e-74: 269: 13.79		PLEC_HUMAN (16-1253): 4.4e-31: 137: 9.18
+	Hs
		166696 DYST_HUMAN (457-866): 1.71e-67: 248: 12.07		CE290_HUMAN (808-2443): 1.12e-32: 142: 10.61
+	Hs
		974137 DYST_HUMAN (457-866): 1.71e-67: 248: 12.07		CP250_HUMAN (1768-2439): 4.39e-10: 67.7: 8.94
+	Mm
		222846 ACK1_MOUSE (9-581): 1.34e-29: 128: 13.93		SPTB2_MOUSE (1408-2420): 1.22e-29: 132: 18.86
+	Dm
		54271 Q9VLS7_DROME (65-706): 2.75e-10: 66.5: 9.08		A1Z9I8_DROME (1-736): 6.78e-29: 130: 17.12
+	Hs
		521586 TITIN_HUMAN (56-404): 7.26e-09: 62.1: 14.93		ACTN1_HUMAN (1862-2210): 3.16e-11: 71.2: 22.25
+	Hs
		211629 TITIN_HUMAN (56-404): 7.26e-09: 62.1: 14.93		ACTN4_HUMAN (1843-2219): 1.15e-09: 66.2: 20.15