HitPredict

Interactor 1: D3YT54 (D3YT54)
Rho-GAP domain-containing protein
Gene: srgp-1

Interactor 2: RAC1 (Q03206)
Ras-related protein ced-10 (CErac1) (Cell death protein 10) (Cell-corpse engulfment protein ced-10) (Ras-related protein rac-1)
Gene: ced-10

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	21170032
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 611 Ce			1 191
+	Ce
		88246 D3YT54_CAEEL (1-611): 2.27e-127: 389: 100.00		CDC42_CAEEL (1-191): 2.85e-77: 230: 70.68
+	Hs
		925395 SRGP1_HUMAN (20-601): 1.88e-94: 315: 24.21		RAC1_HUMAN (1-191): 2.82e-82: 243: 82.81
+	Hs
		200213 SRGP3_HUMAN (20-594): 4.76e-92: 308: 24.12		RAC1_HUMAN (1-191): 2.82e-82: 243: 82.81
+	Hs
		900637 SRGP1_HUMAN (20-601): 1.88e-94: 315: 24.21		RHOA_HUMAN (5-191): 2.1e-77: 231: 56.15
+	Hs
		564562 RHG21_HUMAN (1-595): 9.67e-88: 300: 21.73		RHOQ_HUMAN (4-187): 2.01e-82: 244: 60.87
+	Hs
		925343 RHG21_HUMAN (1-595): 9.67e-88: 300: 21.73		RAC1_HUMAN (1-191): 2.82e-82: 243: 82.81
+	Hs
		925354 RHG17_HUMAN (57-611): 2.01e-88: 294: 16.61		RAC1_HUMAN (1-191): 2.82e-82: 243: 82.81
+	Hs
		951062 RHG21_HUMAN (1-595): 9.67e-88: 300: 21.73		RHOG_HUMAN (1-191): 1.68e-79: 236: 66.49
+	Hs
		545426 RHG21_HUMAN (1-595): 9.67e-88: 300: 21.73		RAC2_HUMAN (1-191): 3.14e-79: 235: 79.17
+	Mm
		892733 SRGP1_MOUSE (20-601): 4.05e-89: 300: 23.42		CDC42_MOUSE (1-191): 1.95e-78: 233: 65.97
+	Hs
		894109 RHG21_HUMAN (1-595): 9.67e-88: 300: 21.73		CDC42_HUMAN (1-191): 1.95e-78: 233: 65.97
+	Hs
		900540 RHG29_HUMAN (2-596): 4.69e-89: 302: 14.62		RHOA_HUMAN (5-191): 2.1e-77: 231: 56.15
+	Mm
		1265268 SRGP1_MOUSE (20-601): 4.05e-89: 300: 23.42		RHOA_MOUSE (5-191): 8e-78: 232: 55.62
+	Hs
		900564 RHG21_HUMAN (1-595): 9.67e-88: 300: 21.73		RHOA_HUMAN (5-191): 2.1e-77: 231: 56.15
+	Hs
		892420 RHG21_HUMAN (1-595): 9.67e-88: 300: 21.73		RAC3_HUMAN (1-177): 1.35e-76: 229: 84.75
+	Mm
		892729 RHG33_MOUSE (4-587): 3.71e-86: 294: 15.28		CDC42_MOUSE (1-191): 1.95e-78: 233: 65.97
+	Hs
		894126 RHG17_HUMAN (57-611): 2.01e-88: 294: 16.61		CDC42_HUMAN (1-191): 1.95e-78: 233: 65.97
+	Hs
		1133703 RHG21_HUMAN (1-595): 9.67e-88: 300: 21.73		RHOJ_HUMAN (2-189): 3.05e-75: 226: 56.38
+	Hs
		147862 RHG33_HUMAN (4-589): 2.25e-82: 283: 14.66		RAC1_HUMAN (1-191): 2.82e-82: 243: 82.81
+	Hs
		64644 RHG32_HUMAN (15-596): 3.94e-81: 281: 17.51		RHOC_HUMAN (5-191): 2.44e-75: 226: 54.55