HitPredict

Interactor 1: BCAR1 (P56945)
Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas)
Gene: BCAR1

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 16105984
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~SH3_1
Common GO terms GO:0005886 - plasma membrane
GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway
GO:0042981 - regulation of apoptotic process
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 870
Hs

1 1620
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024