Interactor 1: BCAR1 (P56945)
Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas)
Gene: BCAR1

Interactor 2: CD2AP (Q9Y5K6)
CD2-associated protein (Adapter protein CMS) (Cas ligand with multiple SH3 domains)
Gene: CD2AP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 10339567, 12618476
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH3_1~SH3_1
Common GO terms GO:0001726 - ruffle
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007015 - actin filament organization
GO:0015629 - actin cytoskeleton
and 6 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 870
Hs

1 639
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024