HitPredict

Interactor 1: UBS3A (P57075)
Ubiquitin-associated and SH3 domain-containing protein A (Cbl-interacting protein 4) (CLIP4) (Suppressor of T-cell receptor signaling 2) (STS-2) (T-cell ubiquitin ligand 1) (TULA-1)
Gene: UBASH3A

Interactor 2: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 661 Hs			1 669
+	Hs
		883402 UBS3A_HUMAN (1-661): 0: 1048: 100.00		LZTS1_HUMAN (26-653): 2.54e-34: 140: 35.06
+	Hs
		165760 UBS3A_HUMAN (1-661): 0: 1048: 100.00		N4BP3_HUMAN (17-640): 5.23e-34: 139: 27.16
+	Hs
		883336 UBS3A_HUMAN (1-661): 0: 1048: 100.00		DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41
+	Hs
		1257132 UBS3B_HUMAN (1-655): 0: 904: 43.07		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		725206 UBS3B_HUMAN (1-655): 0: 904: 43.07		MYH10_HUMAN (321-640): 8.77e-09: 61.2: 18.79
+	Hs
		1060050 LASP1_HUMAN (163-337): 3.87e-36: 138: 17.11		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		282366 NEBL_HUMAN (188-340): 7.6e-29: 124: 20.12		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		1256102 SH3R2_HUMAN (255-386): 1.63e-25: 114: 20.46		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		997493 Q08AM8_HUMAN (255-386): 1.53e-25: 114: 20.46		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		298998 SRBS2_HUMAN (200-339): 2.17e-23: 107: 22.37		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		1310117 SRBS1_HUMAN (145-339): 1.51e-20: 99.1: 21.46		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		1051278 LASP1_HUMAN (163-337): 3.87e-36: 138: 17.11		DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41
+	Hs
		282331 NEBL_HUMAN (188-340): 7.6e-29: 124: 20.12		DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41
+	Hs
		298992 SRBS2_HUMAN (200-339): 2.17e-23: 107: 22.37		MY18A_HUMAN (329-637): 1.72e-11: 70: 17.67
+	Hs
		924566 GRB2_HUMAN (245-341): 1.31e-22: 98.4: 25.25		DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41
+	Hs
		924736 GRB2_HUMAN (245-341): 1.31e-22: 98.4: 25.25		MY18A_HUMAN (329-637): 1.72e-11: 70: 17.67
+	Hs
		148235 SRBS2_HUMAN (200-339): 2.17e-23: 107: 22.37		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		728465 GRB2_HUMAN (245-341): 1.31e-22: 98.4: 25.25		MYH11_HUMAN (141-564): 3.93e-11: 68.9: 11.53
+	Hs
		924586 GRB2_HUMAN (245-341): 1.31e-22: 98.4: 25.25		PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77
+	Hs
		725134 GRB2_HUMAN (245-341): 1.31e-22: 98.4: 25.25		MYH10_HUMAN (321-640): 8.77e-09: 61.2: 18.79