Protein: HPPD
4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) (4-hydroxyphenylpyruvic acid oxidase) (4HPPD) (HPD) (HPPDase)

Gene: HPPD, HPD
Organism: Homo sapiens
Interactions: 18
UniProt ID: P32754

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0003868 - 4-hydroxyphenylpyruvate dioxygenase activity
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0006559 - L-phenylalanine catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

744477

RBMX
RNA-binding motif protein, X chromosome

3

0

High-throughput

0.638

High

744486

ASPC1
Tether containing UBX domain for GLUT4

2

0

High-throughput

0.576

High

744489

NEMO
NF-kappa-B essential modulator

1

1

High-throughput

0.541

High

744478

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.518

High

744487

RTN4
Reticulon-4

1

0

High-throughput

0.513

High

744485

STK33
Serine/threonine-protein kinase 33

1

1

Small-scale

0.512

High

744484

PELI1
E3 ubiquitin-protein ligase pellino homolog 1

1

1

Small-scale

0.479

High

586235

ZEP1
Zinc finger protein 40

1

0

High-throughput

0.460

High

744481

RIDA
2-iminobutanoate/2-iminopropanoate deaminase

1

0

High-throughput

0.460

High

428300

RLA2
Large ribosomal subunit protein P2

1

0

High-throughput

0.458

High

587570

DESP
Desmoplakin

1

0

Small-scale

0.458

High

744479

RL13A
Large ribosomal subunit protein uL13

1

0

High-throughput

0.458

High

744480

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.458

High

744483

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.458

High

744488

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

0

Small-scale

0.458

High

66828

TTC36
Tetratricopeptide repeat protein 36

1

3

Small-scale

0.437

High

522382

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

0

Small-scale

0.249

Low

744482

GTF2I
General transcription factor II-I

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025