HitPredict

Interactor 1: KLF3 (P57682)
Krueppel-like factor 3 (Basic krueppel-like factor) (CACCC-box-binding protein BKLF) (TEF-2)
Gene: KLF3

Interactor 2: TLE5 (Q08117)
TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) (TLE family member 5, transcriptional modulator)
Gene: TLE5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 345 Hs			1 197
+	Hs
		884133 KLF3_HUMAN (1-345): 4.46e-98: 295: 100.00		TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50
+	Hs
		884134 KLF3_HUMAN (1-345): 4.46e-98: 295: 100.00		TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50
+	Hs
		316865 KLF8_HUMAN (1-342): 9.85e-87: 267: 36.99		TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00
+	Hs
		993497 ZNF34_HUMAN (33-344): 4.1e-81: 258: 14.82		TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00
+	Hs
		993504 ZN383_HUMAN (13-233): 2.47e-79: 251: 8.44		TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00
+	Hs
		980959 KLF12_HUMAN (239-345): 1.44e-52: 180: 83.18		TLE4_HUMAN (2-191): 3.57e-112: 338: 68.59
+	Hs
		980601 KLF5_HUMAN (217-342): 5.6e-39: 145: 63.36		TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50
+	Hs
		204165 KLF4_HUMAN (223-342): 2.87e-35: 136: 60.00		TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50
+	Hs
		980748 KLF5_HUMAN (217-342): 5.6e-39: 145: 63.36		TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50
+	Hs
		993418 KLF5_HUMAN (217-342): 5.6e-39: 145: 63.36		TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00
+	Hs
		204169 KLF4_HUMAN (223-342): 2.87e-35: 136: 60.00		TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00
+	Hs
		993414 KLF1_HUMAN (254-343): 2.2e-36: 136: 71.11		TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00
+	Ce
		137695 KLF1_CAEEL (245-342): 2.43e-37: 141: 66.00		UNC37_CAEEL (18-160): 8.43e-43: 153: 28.47