HitPredict

Interactor 1: RAB25 (P57735)
Ras-related protein Rab-25 (CATX-8)
Gene: RAB25

Interactor 2: RAP1B (P61224)
Ras-related protein Rap-1b (EC 3.6.5.2) (GTP-binding protein smg p21B)
Gene: RAP1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37232246
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 213 Hs			1 184
+	Zm
		73944 B4FAE1_MAIZE (6-211): 2.22e-90: 265: 40.78		B4FAE1_MAIZE (4-180): 5.71e-75: 225: 35.39
+	Hs
		918846 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RAB1A_HUMAN (4-183): 4.68e-73: 220: 31.49
+	Hs
		897876 RB11A_HUMAN (1-213): 1.11e-87: 259: 60.37		RAP1B_HUMAN (1-184): 3.62e-74: 222: 100.00
+	Hs
		918879 RB11B_HUMAN (1-213): 4.74e-88: 260: 58.90		RAB1A_HUMAN (4-183): 4.68e-73: 220: 31.49
+	Hs
		918944 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RAB1B_HUMAN (4-179): 4.82e-71: 215: 29.94
+	Mm
		919000 RAB1A_MOUSE (1-210): 3.08e-89: 262: 39.05		RAB1B_MOUSE (4-179): 1.21e-70: 214: 29.94
+	Hs
		1079964 RB11B_HUMAN (1-213): 4.74e-88: 260: 58.90		RAB1B_HUMAN (4-179): 4.82e-71: 215: 29.94
+	Hs
		913992 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RB11A_HUMAN (4-178): 2.05e-69: 211: 28.98
+	Hs
		914093 RB11B_HUMAN (1-213): 4.74e-88: 260: 58.90		RB11A_HUMAN (4-178): 2.05e-69: 211: 28.98
+	Hs
		918847 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55
+	Hs
		913989 RB11A_HUMAN (1-213): 1.11e-87: 259: 60.37		RB11A_HUMAN (4-178): 2.05e-69: 211: 28.98
+	Hs
		925305 RB11B_HUMAN (1-213): 4.74e-88: 260: 58.90		RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55
+	Hs
		349231 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RASH_HUMAN (1-167): 1.22e-55: 175: 57.49
+	Hs
		350037 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RASK_HUMAN (1-167): 6.26e-55: 174: 57.49
+	Hs
		349344 RB11B_HUMAN (1-213): 4.74e-88: 260: 58.90		RASH_HUMAN (1-167): 1.22e-55: 175: 57.49
+	Hs
		350197 RB11B_HUMAN (1-213): 4.74e-88: 260: 58.90		RASK_HUMAN (1-167): 6.26e-55: 174: 57.49
+	Hs
		348601 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RASN_HUMAN (1-167): 5.03e-54: 171: 56.89
+	Hs
		350033 RB11A_HUMAN (1-213): 1.11e-87: 259: 60.37		RASK_HUMAN (1-167): 6.26e-55: 174: 57.49
+	Hs
		348682 RB11B_HUMAN (1-213): 4.74e-88: 260: 58.90		RASN_HUMAN (1-167): 5.03e-54: 171: 56.89