HitPredict

Interactor 1: RAB25 (P57735)
Ras-related protein Rab-25 (CATX-8)
Gene: RAB25

Interactor 2: EFC4B (Q9BSW2)
EF-hand calcium-binding domain-containing protein 4B (Calcium release-activated calcium channel regulator 2A) (CRAC channel regulator 2A) (Calcium release-activated channel regulator 2A) (Ras-related protein Rab-46)
Gene: CRACR2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37232246
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 213 Hs			1 731
+	Hs
		914201 RB11A_HUMAN (1-213): 1.11e-87: 259: 60.37		RASEF_HUMAN (44-730): 2.81e-94: 310: 25.47
+	Hs
		914319 RB11A_HUMAN (1-213): 1.11e-87: 259: 60.37		EFC4B_HUMAN (1-731): 8.94e-91: 301: 100.00
+	Zm
		73944 B4FAE1_MAIZE (6-211): 2.22e-90: 265: 40.78		B4FAE1_MAIZE (538-730): 5.97e-87: 274: 33.17
+	Hs
		918846 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RAB1A_HUMAN (535-730): 1.67e-84: 267: 31.71
+	Hs
		918879 RB11B_HUMAN (1-213): 4.74e-88: 260: 58.90		RAB1A_HUMAN (535-730): 1.67e-84: 267: 31.71
+	Hs
		913992 RB11A_HUMAN (1-213): 1.11e-87: 259: 60.37		RAB1A_HUMAN (535-730): 1.67e-84: 267: 31.71
+	Hs
		918944 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RAB1B_HUMAN (538-730): 5.45e-83: 263: 30.85
+	Mm
		919000 RAB1A_MOUSE (1-210): 3.08e-89: 262: 39.05		RAB1B_MOUSE (538-730): 7.32e-83: 263: 30.85
+	Hs
		1079964 RB11B_HUMAN (1-213): 4.74e-88: 260: 58.90		RAB1B_HUMAN (538-730): 5.45e-83: 263: 30.85
+	Hs
		895472 RB11A_HUMAN (1-213): 1.11e-87: 259: 60.37		RAB10_HUMAN (546-730): 5.1e-83: 263: 36.65
+	Hs
		895549 RAB1B_HUMAN (6-210): 4.92e-87: 257: 40.98		RAB10_HUMAN (546-730): 5.1e-83: 263: 36.65
+	Hs
		918874 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RAB35_HUMAN (538-730): 3.7e-81: 258: 32.67
+	Mm
		918986 RAB1A_MOUSE (1-210): 3.08e-89: 262: 39.05		RAB35_MOUSE (538-730): 3.7e-81: 258: 32.67
+	Hs
		894715 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RAB8A_HUMAN (538-727): 1.07e-79: 255: 37.90
+	Hs
		894712 RB11A_HUMAN (1-213): 1.11e-87: 259: 60.37		RAB8A_HUMAN (538-727): 1.07e-79: 255: 37.90
+	Hs
		591540 RAB1A_HUMAN (1-210): 3.08e-89: 262: 39.05		RAB3B_HUMAN (535-702): 8.54e-41: 150: 43.45
+	Hs
		845845 RB11A_HUMAN (1-213): 1.11e-87: 259: 60.37		RAB13_HUMAN (541-704): 9.47e-42: 152: 42.68
+	Hs
		591578 RB11B_HUMAN (1-213): 4.74e-88: 260: 58.90		RAB3B_HUMAN (535-702): 8.54e-41: 150: 43.45
+	Hs
		591538 RB11A_HUMAN (1-213): 1.11e-87: 259: 60.37		RAB3B_HUMAN (535-702): 8.54e-41: 150: 43.45
+	Hs
		845881 RAB1B_HUMAN (6-210): 4.92e-87: 257: 40.98		RAB13_HUMAN (541-704): 9.47e-42: 152: 42.68