HitPredict

Interactor 1: SESN2 (P58004)
Sestrin-2 (EC 1.11.1.-) (Hypoxia-induced gene)
Gene: SESN2

Interactor 2: NPRL3 (Q12980)
GATOR1 complex protein NPRL3 (-14 gene protein) (Alpha-globin regulatory element-containing gene protein) (Nitrogen permease regulator 3-like protein) (Protein CGTHBA)
Gene: NPRL3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.634

Property	Details
Experiments	28199315, 25263562
Identification Methods	affinity chromatography technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005765 - lysosomal membrane GO:0034198 - cellular response to amino acid starvation GO:1904262 - negative regulation of TORC1 signaling
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 480 Hs			1 569
+	Hs
		885144 SESN3_HUMAN (29-480): 0: 770: 56.60		NPRL3_HUMAN (1-569): 0: 789: 100.00