Interactor 1: SESN2 (P58004)
Sestrin-2 (EC 1.11.1.-) (Hypoxia-induced gene)
Gene: SESN2
Interactor 2: WDR24 (Q96S15)
GATOR2 complex protein WDR24 (EC 2.3.2.27) (WD repeat-containing protein 24)
Gene: WDR24
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 0.60 | 0.752 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25263562, 28199315, 35114100, 35831510, 26449471, 26586190, 26972053 |
| Identification Methods | affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005765 - lysosomal membrane GO:0005829 - cytosol GO:0016239 - positive regulation of macroautophagy GO:0034198 - cellular response to amino acid starvation GO:1904262 - negative regulation of TORC1 signaling and 1 others more... |
| Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
