HitPredict

Interactor 1: SESN2 (P58004)
Sestrin-2 (EC 1.11.1.-) (Hypoxia-induced gene)
Gene: SESN2

Interactor 2: MIOS (Q9NXC5)
GATOR2 complex protein MIOS (Missing oocyte meiosis regulator homolog)
Gene: MIOS

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 0.60 0.723

The method score is based on:

Property Details
Experiments 25263562, 28199315, 35831510, 35114100, 26586190
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0034198 - cellular response to amino acid starvation
GO:1904262 - negative regulation of TORC1 signaling
and 1 others

more...
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 480
Hs

1 875
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024