HitPredict

Interactor 1: D3ZC56 (D3ZC56)
Dystonin
Gene: Dst

Interactor 2: INSR (P15127)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Species: Rattus norvegicus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	30300385
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	CH~fn3, CH~PK_Tyr_Ser-Thr
Common GO terms	GO:0005198 - structural molecule activity GO:0016020 - membrane GO:0030424 - axon
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 7512 Rn			1 1383
+	Hs
		665392 DYST_HUMAN (1-7512): 0: 2472: 78.40		EPHA3_HUMAN (661-1320): 4.01e-172: 541: 24.15
+	Hs
		665216 DYST_HUMAN (1-7512): 0: 2472: 78.40		EPHA2_HUMAN (662-1321): 2.76e-167: 528: 22.70
+	Hs
		666578 DYST_HUMAN (1-7512): 0: 2472: 78.40		LTK_HUMAN (1014-1292): 4.56e-70: 255: 43.82
+	Hs
		974084 DYST_HUMAN (1-7512): 0: 2472: 78.40		NTRK2_HUMAN (997-1293): 1.8e-67: 246: 42.72
+	Hs
		384681 DYST_HUMAN (1-7512): 0: 2472: 78.40		NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95
+	Hs
		383754 DYST_HUMAN (1-7512): 0: 2472: 78.40		ERBB2_HUMAN (32-342): 4.75e-18: 92.8: 19.83
+	Rn
		102506 UTRN_RAT (370-1542): 4.08e-20: 102: 10.85		INSR_RAT (1-1383): 0: 1575: 100.00
+	Hs
		666598 GOGB1_HUMAN (252-1119): 9.83e-13: 78.2: 10.52		LTK_HUMAN (1014-1292): 4.56e-70: 255: 43.82
+	Hs
		169189 SYNE1_HUMAN (230-1714): 8.62e-13: 78.6: 9.76		MUSK_HUMAN (1018-1292): 3.32e-69: 253: 42.22
+	Hs
		384662 SPTB2_HUMAN (3009-4428): 1.16e-16: 91.3: 8.52		NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95
+	Hs
		384210 DESP_HUMAN (1753-1991): 1.42e-13: 81.3: 17.99		NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95
+	Hs
		385192 SYNE1_HUMAN (230-1714): 8.62e-13: 78.6: 9.76		NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95
+	Hs
		384810 SPTN1_HUMAN (284-885): 9.95e-13: 78.4: 12.95		NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95
+	Hs
		609206 UTRN_HUMAN (275-1545): 6.19e-15: 85.5: 9.61		FGFR3_HUMAN (1016-1288): 2.88e-60: 224: 40.07
+	Hs
		384183 ACTN1_HUMAN (6393-6864): 9.96e-09: 64.7: 11.80		NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95
+	Hs
		601922 GOGB1_HUMAN (252-1119): 9.83e-13: 78.2: 10.52		ERBB3_HUMAN (5-368): 5.74e-31: 135: 19.70
+	Hs
		338405 SPTN1_HUMAN (284-885): 9.95e-13: 78.4: 12.95		EGFR_HUMAN (32-308): 1.21e-29: 130: 22.50
+	Hs
		338442 GOGB1_HUMAN (252-1119): 9.83e-13: 78.2: 10.52		EGFR_HUMAN (32-308): 1.21e-29: 130: 22.50
+	Hs
		383972 SPTN4_HUMAN (3012-4382): 6.97e-09: 65.5: 9.38		ERBB2_HUMAN (32-342): 4.75e-18: 92.8: 19.83