Interactor 1: D3ZB14 (D3ZB14)
CASP2 and RIPK1 domain containing adaptor with death domain
Gene: Cradd
Interactor 2: CASP2 (P55215)
Caspase-2 (CASP-2) (EC 3.4.22.55) (Protease ICH-1) [Cleaved into: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12]
Gene: CASP2
Species: Rattus norvegicus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.646 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18845684 |
| Identification Methods | anti bait coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CARD~CARD |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0006977 - DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0043065 - positive regulation of apoptotic process GO:0071260 - cellular response to mechanical stimulus and 3 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
