HitPredict

Interactor 1: MTPN (P58546)
Myotrophin (Protein V-1)
Gene: MTPN

Interactor 2: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	1.00	0.724

Property	Details
Experiments	11971907
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ank_2~RHD_dimer
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0051092 - positive regulation of NF-kappaB transcription factor activity
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 118 Hs			1 551
+	Hs
		978869 BARD1_HUMAN (31-118): 2.19e-31: 118: 27.27		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		276172 PSD10_HUMAN (64-118): 4.1e-15: 69.9: 21.82		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		978897 EHMT1_HUMAN (2-49): 3.3e-09: 54.8: 22.92		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		885778 MTPN_HUMAN (1-118): 5.13e-42: 135: 100.00		REL_HUMAN (12-523): 3.56e-165: 484: 41.64
+	Hs
		587486 MTPN_HUMAN (1-118): 5.13e-42: 135: 100.00		NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51
+	Hs
		587690 BARD1_HUMAN (31-118): 2.19e-31: 118: 27.27		NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51
+	Hs
		276140 PSD10_HUMAN (64-118): 4.1e-15: 69.9: 21.82		NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51
+	Hs
		587628 ANKH1_HUMAN (2-93): 1.32e-10: 58.9: 35.87		NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51
+	Hs
		166934 ANR28_HUMAN (12-93): 8.44e-09: 53.5: 34.15		NFAC4_HUMAN (5-461): 5.79e-101: 326: 17.82