HitPredict

Interactor 1: MTPN (P58546)
Myotrophin (Protein V-1)
Gene: MTPN

Interactor 2: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36517590
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 118 Hs			1 746
+	Hs
		1080355 EHMT1_HUMAN (2-49): 3.3e-09: 54.8: 22.92		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		166937 ANR28_HUMAN (12-93): 8.44e-09: 53.5: 34.15		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Mm
		1125426 EHMT1_MOUSE (2-49): 5.84e-09: 54.1: 22.92		EZH2_MOUSE (1-746): 0: 860: 98.39
+	Mm
		936645 EHMT1_MOUSE (2-49): 5.84e-09: 54.1: 22.92		EZH1_MOUSE (15-745): 0: 755: 63.61
+	Sc
		755773 HOS4_YEAST (3-71): 3.44e-17: 77.8: 26.76		SET1_YEAST (205-733): 1.13e-84: 292: 16.01
+	Hs
		1334130 EHMT1_HUMAN (2-49): 3.3e-09: 54.8: 22.92		EHMT1_HUMAN (441-732): 1.73e-70: 253: 24.27
+	Hs
		1296421 EHMT1_HUMAN (2-49): 3.3e-09: 54.8: 22.92		EHMT2_HUMAN (467-732): 1.91e-68: 247: 24.21
+	Hs
		1331975 EHMT1_HUMAN (2-49): 3.3e-09: 54.8: 22.92		SUV92_HUMAN (447-734): 5.41e-74: 247: 24.10
+	Mm
		1125434 EHMT1_MOUSE (2-49): 5.84e-09: 54.1: 22.92		EHMT2_MOUSE (467-732): 2.28e-68: 247: 24.56
+	Hs
		166998 ANR28_HUMAN (12-93): 8.44e-09: 53.5: 34.15		EHMT2_HUMAN (467-732): 1.91e-68: 247: 24.21
+	Hs
		203794 EHMT1_HUMAN (2-49): 3.3e-09: 54.8: 22.92		SUV91_HUMAN (354-731): 2.25e-71: 240: 19.90