HitPredict

Interactor 1: D3ZHL1 (D3ZHL1)
Kinase suppressor of ras 1
Gene: Ksr1

Interactor 2: MP2K1 (Q01986)
Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)
Gene: Map2k1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 10409742
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~Pkinase
Common GO terms GO:0005078 - MAP-kinase scaffold activity
GO:0005524 - ATP binding
GO:0005783 - endoplasmic reticulum
GO:0016020 - membrane
GO:0019901 - protein kinase binding
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 888
Rn

1 393
+ Rn
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+ Hs
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+ Dm
+ Dm
+ Hs
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+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024