HitPredict

Interactor 1: NAL12 (P59046)
NACHT, LRR and PYD domains-containing protein 12 (Monarch-1) (PYRIN-containing APAF1-like protein 7) (Regulated by nitric oxide)
Gene: NLRP12

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25036637
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030674 - protein-macromolecule adaptor activity
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1061 Hs			1 303
+	Hs
		886421 NAL12_HUMAN (1-1061): 0: 818: 100.00		Q9BPW0_HUMAN (1-259): 2.98e-36: 137: 20.91
+	Hs
		213515 NAL12_HUMAN (1-1061): 0: 818: 100.00		SGTA_HUMAN (3-140): 2.4e-33: 126: 29.71
+	Hs
		1299045 NLRP3_HUMAN (806-1060): 1.1e-44: 177: 45.10		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		1335697 NOD2_HUMAN (857-1061): 3.5e-19: 95.9: 25.37		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Mm
		1194757 PPR37_MOUSE (623-978): 7.19e-34: 141: 22.01		WDTC1_MOUSE (21-272): 7.36e-30: 120: 19.22
+	Hs
		1166870 LRC31_HUMAN (595-849): 3.54e-12: 72.5: 20.35		UN45A_HUMAN (15-161): 8.39e-42: 155: 29.30
+	Hs
		1308528 NOD1_HUMAN (631-842): 4.27e-16: 85.5: 21.36		Q9BPW0_HUMAN (1-259): 2.98e-36: 137: 20.91