HitPredict

Interactor 1: LMBL2 (P59178)
Lethal(3)malignant brain tumor-like protein 2 (L(3)mbt-like protein 2)
Gene: L3mbtl2

Interactor 2: HDAC2 (P70288)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-) (YY1 transcription factor-binding protein)
Gene: HDAC2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22770845
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0006325 - chromatin organization GO:0045892 - negative regulation of DNA-templated transcription GO:1990841 - promoter-specific chromatin binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 703 Mm			1 488
+	Hs
		1270359 LMBL2_HUMAN (1-703): 0: 1015: 90.92		HDAC2_HUMAN (1-488): 0: 707: 99.39
+	Mm
		140246 LMBL2_MOUSE (1-703): 0: 1029: 100.00		HDAC1_MOUSE (1-446): 0: 647: 89.46
+	Hs
		1038604 LMBL2_HUMAN (1-703): 0: 1015: 90.92		HDAC1_HUMAN (1-446): 0: 643: 89.24
+	Hs
		177350 LMBL2_HUMAN (1-703): 0: 1015: 90.92		HDAC3_HUMAN (10-431): 0: 575: 58.02
+	Hs
		1270507 SMBT1_HUMAN (159-638): 0: 562: 32.12		HDAC2_HUMAN (1-488): 0: 707: 99.39
+	Hs
		1038787 SMBT1_HUMAN (159-638): 0: 562: 32.12		HDAC1_HUMAN (1-446): 0: 643: 89.24
+	Hs
		1270377 LMBL3_HUMAN (140-285): 2.03e-26: 117: 26.03		HDAC2_HUMAN (1-488): 0: 707: 99.39
+	Dm
		1276540 SMBT_DROME (138-401): 4.29e-35: 145: 21.53		HDAC1_DROME (5-472): 0: 654: 77.71
+	Hs
		1038627 LMBL3_HUMAN (140-285): 2.03e-26: 117: 26.03		HDAC1_HUMAN (1-446): 0: 643: 89.24
+	Dm
		1276533 Q9VB52_DROME (148-294): 3.4e-17: 88.3: 23.13		HDAC1_DROME (5-472): 0: 654: 77.71