HitPredict

Interactor 1: NPHP4 (P59240)
Nephrocystin-4 (Nephroretinin)
Gene: NPHP4

Interactor 2: K22E (Q3TTY5)
Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (CK-2e) (Epithelial keratin-2e) (Keratin-2 epidermis) (Keratin-2e) (K2e) (Type-II keratin Kb2)
Gene: Krt2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21565611
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1425 Mm			1 707
+	Mm
		886750 NPHP4_MOUSE (1-1425): 0: 2360: 100.00		K2C1B_MOUSE (166-514): 1.5e-165: 489: 67.34
+	Mm
		514318 NPHP4_MOUSE (1-1425): 0: 2360: 100.00		K2C8_MOUSE (171-570): 1.07e-163: 481: 55.25
+	Mm
		886824 NPHP4_MOUSE (1-1425): 0: 2360: 100.00		K2C7_MOUSE (164-577): 9.1e-131: 396: 53.59
+	Mm
		886748 NPHP4_MOUSE (1-1425): 0: 2360: 100.00		Q6IFT3_MOUSE (89-702): 3.95e-83: 281: 41.42
+	Mm
		886713 NPHP4_MOUSE (1-1425): 0: 2360: 100.00		KRT86_MOUSE (92-514): 9.02e-81: 267: 44.10
+	Mm
		886752 NPHP4_MOUSE (1-1425): 0: 2360: 100.00		K2C73_MOUSE (74-517): 1.32e-79: 265: 56.08
+	Mm
		839461 NPHP4_MOUSE (1-1425): 0: 2360: 100.00		K2C6A_MOUSE (63-529): 1.26e-76: 258: 57.26
+	Mm
		886810 NPHP4_MOUSE (1-1425): 0: 2360: 100.00		K2C5_MOUSE (9-515): 1.38e-73: 250: 55.38
+	Mm
		886725 NPHP4_MOUSE (1-1425): 0: 2360: 100.00		K22O_MOUSE (9-626): 8.2e-72: 246: 51.61
+	Mm
		886801 NPHP4_MOUSE (1-1425): 0: 2360: 100.00		K2C79_MOUSE (131-524): 1.14e-70: 241: 59.24
+	Mm
		886812 NPHP4_MOUSE (1-1425): 0: 2360: 100.00		KRT82_MOUSE (245-582): 8.67e-09: 60.7: 10.98