Interactor 1: ARPC4 (P59998)
Actin-related protein 2/3 complex subunit 4 (Arp2/3 complex 20 kDa subunit) (p20-ARC)
Gene: ARPC4

Interactor 2: ARP5L (Q9BPX5)
Actin-related protein 2/3 complex subunit 5-like protein (Arp2/3 complex 16 kDa subunit 2) (ARC16-2)
Gene: ARPC5L

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 30021884, 33961781, 35235311, 34349018, 37071682, 16169070, 32296183, 24981860, 26655834, unassigned1304
Identification Methods proximity labelling technology, affinity chromatography technology, cross-linking study, two hybrid, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid, tandem affinity purification, two hybrid pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ARPC4~P16-Arc
Common GO terms GO:0005885 - Arp2/3 protein complex
GO:0034314 - Arp2/3 complex-mediated actin nucleation
GO:0051015 - actin filament binding
GO:0070062 - extracellular exosome
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 168
Hs

1 153
+ Hs
+ Dm
+ At
+ Sp
+ Sc

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Last updated: 15 Jul 2024