HitPredict

Interactor 1: D3ZUY8 (D3ZUY8)
AP-2 complex subunit alpha
Gene: Ap2a1

Interactor 2: BIN1 (O08839)
Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Bridging integrator 1)
Gene: BIN1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	11382783
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0044877 - protein-containing complex binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 956 Rn			1 588
+	Rn
		139993 Q66HM2_RAT (1-956): 0: 836: 80.19		BIN1_RAT (1-588): 4.99e-132: 400: 100.00
+	Hs
		131189 AP2A1_HUMAN (1-956): 0: 858: 95.09		BIN1_HUMAN (1-587): 1.85e-121: 373: 93.76
+	Hs
		131185 AP2A2_HUMAN (1-956): 0: 822: 79.08		BIN1_HUMAN (1-587): 1.85e-121: 373: 93.76
+	Rn
		139988 AP2B1_RAT (36-951): 0: 654: 17.03		BIN1_RAT (1-588): 4.99e-132: 400: 100.00
+	Rn
		88753 D3ZUY8_RAT (1-956): 0: 885: 100.00		AMPH_RAT (91-588): 1.14e-11: 69.5: 16.51
+	Hs
		321511 AP2A1_HUMAN (1-956): 0: 858: 95.09		AMPH_HUMAN (43-588): 1.53e-15: 82.2: 16.97
+	Hs
		203194 AP2A1_HUMAN (1-956): 0: 858: 95.09		SYNJ1_HUMAN (162-550): 1.33e-14: 79.5: 10.72
+	Rn
		1144064 Q66HM2_RAT (1-956): 0: 836: 80.19		SYNJ1_RAT (156-585): 1.28e-15: 83: 12.04
+	Mm
		567528 AP2A2_MOUSE (1-956): 0: 832: 80.94		AMPH_MOUSE (43-588): 1.62e-14: 78.8: 17.03
+	Rn
		139980 Q66HM2_RAT (1-956): 0: 836: 80.19		AMPH_RAT (91-588): 1.14e-11: 69.5: 16.51
+	Hs
		302118 AP2A2_HUMAN (1-956): 0: 822: 79.08		AMPH_HUMAN (43-588): 1.53e-15: 82.2: 16.97
+	Hs
		827733 AP2B1_HUMAN (36-951): 0: 654: 17.03		AMPH_HUMAN (43-588): 1.53e-15: 82.2: 16.97
+	Hs
		203219 AP2B1_HUMAN (36-951): 0: 654: 17.03		SYNJ1_HUMAN (162-550): 1.33e-14: 79.5: 10.72
+	Mm
		1186720 AP2B1_MOUSE (36-951): 0: 653: 17.03		AMPH_MOUSE (43-588): 1.62e-14: 78.8: 17.03
+	Hs
		827743 AP1B1_HUMAN (36-951): 0: 647: 17.33		AMPH_HUMAN (43-588): 1.53e-15: 82.2: 16.97
+	Hs
		203223 AP1B1_HUMAN (36-951): 0: 647: 17.33		SYNJ1_HUMAN (162-550): 1.33e-14: 79.5: 10.72
+	Rn
		139975 AP2B1_RAT (36-951): 0: 654: 17.03		AMPH_RAT (91-588): 1.14e-11: 69.5: 16.51
+	Hs
		212606 AP1G1_HUMAN (1-829): 0: 596: 24.53		AMPH_HUMAN (43-588): 1.53e-15: 82.2: 16.97
+	Sc
		764159 AP3D_YEAST (51-455): 4.1e-16: 85.5: 22.52		RV167_YEAST (16-383): 3.27e-41: 157: 14.43
+	Sc
		758554 AP3D_YEAST (51-455): 4.1e-16: 85.5: 22.52		SEC31_YEAST (161-536): 7.83e-09: 61: 11.05