HitPredict

Interactor 1: D3ZUY8 (D3ZUY8)
AP-2 complex subunit alpha
Gene: Ap2a1

Interactor 2: NECP1 (P69682)
Adaptin ear-binding coat-associated protein 1 (NECAP endocytosis-associated protein 1) (NECAP-1)
Gene: Necap1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	16903783
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Adaptin_N~DUF1681
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 956 Rn			1 277
+	Hs
		321598 AP2A1_HUMAN (1-956): 0: 858: 95.09		NECP1_HUMAN (1-277): 7.94e-164: 456: 92.42
+	Mm
		567534 AP2A2_MOUSE (1-956): 0: 832: 80.94		NECP1_MOUSE (1-277): 8.75e-163: 454: 97.11
+	Rn
		935895 Q66HM2_RAT (1-956): 0: 836: 80.19		NECP1_RAT (1-277): 2.28e-158: 443: 100.00
+	Hs
		302186 AP2A2_HUMAN (1-956): 0: 822: 79.08		NECP1_HUMAN (1-277): 7.94e-164: 456: 92.42
+	Hs
		321655 AP2A1_HUMAN (1-956): 0: 858: 95.09		NECP2_HUMAN (4-277): 1.13e-143: 405: 61.51
+	Hs
		302215 AP2A2_HUMAN (1-956): 0: 822: 79.08		NECP2_HUMAN (4-277): 1.13e-143: 405: 61.51
+	Hs
		925949 AP2B1_HUMAN (36-951): 0: 654: 17.03		NECP1_HUMAN (1-277): 7.94e-164: 456: 92.42
+	Hs
		1014052 AP1B1_HUMAN (36-951): 0: 647: 17.33		NECP1_HUMAN (1-277): 7.94e-164: 456: 92.42
+	Hs
		926024 AP2B1_HUMAN (36-951): 0: 654: 17.03		NECP2_HUMAN (4-277): 1.13e-143: 405: 61.51
+	Hs
		1014091 AP1B1_HUMAN (36-951): 0: 647: 17.33		NECP2_HUMAN (4-277): 1.13e-143: 405: 61.51
+	Hs
		212648 AP1G1_HUMAN (1-829): 0: 596: 24.53		NECP1_HUMAN (1-277): 7.94e-164: 456: 92.42
+	Hs
		212666 AP1G1_HUMAN (1-829): 0: 596: 24.53		NECP2_HUMAN (4-277): 1.13e-143: 405: 61.51