Interactor 1: D3ZV15 (D3ZV15)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27)
Gene: Cbl

Interactor 2: IRS1 (P35570)
Insulin receptor substrate 1 (IRS-1) (pp185)
Gene: IRS1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 19546233
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001784 - phosphotyrosine residue binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0014823 - response to activity
GO:0019901 - protein kinase binding
and 1 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 894
Rn

1 1235
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Dm
+ Hs
+ Hs

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Last updated: 15 Jul 2024