HitPredict

Interactor 1: D3ZV15 (D3ZV15)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27)
Gene: Cbl

Interactor 2: UBC (Q63429)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]
Gene: UBC

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20029031
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cbl_N3~ubiquitin, ubiquitin~zf-C3HC4
Common GO terms	GO:0006511 - ubiquitin-dependent protein catabolic process GO:0016567 - protein ubiquitination
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 894 Rn			1 810
+	Hs
		475339 CBL_HUMAN (1-851): 0: 844: 91.56		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		475700 CBLB_HUMAN (23-727): 0: 726: 56.50		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		476560 CBLC_HUMAN (42-503): 0: 625: 42.16		UBC_HUMAN (1-533): 0: 662: 99.81
+	Rn
		1144063 SYNJ1_RAT (552-883): 2.23e-09: 63.8: 12.65		UBC_RAT (1-810): 0: 1000: 100.00
+	Hs
		610336 CBL_HUMAN (1-851): 0: 844: 91.56		RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00
+	Mm
		476784 CBLB_MOUSE (23-727): 0: 735: 56.77		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Hs
		475943 OTOG_HUMAN (401-871): 5.65e-20: 98.5: 12.01		UBC_HUMAN (1-533): 0: 662: 99.81
+	At
		1092229 SC24C_ARATH (425-797): 9.2e-14: 77.7: 12.77		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	At
		1092118 Q9LIE8_ARATH (381-662): 9.3e-11: 68.1: 8.80		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	Hs
		397931 ZO1_HUMAN (436-894): 5.74e-24: 111: 15.35		ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69