Interactor 1: D3ZVH5 (D3ZVH5)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27)
Gene: Mdm2

Interactor 2: HIF1A (O35800)
Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha)
Gene: HIF1A

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 19950214
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001568 - blood vessel development
GO:0002039 - p53 binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 15 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 458
Rn

1 825
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024