HitPredict

Interactor 1: CD81 (P60033)
CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the antiproliferative antibody 1) (Tetraspanin-28) (Tspan-28) (CD antigen CD81)
Gene: CD81

Interactor 2: VAMP3 (Q15836)
Vesicle-associated membrane protein 3 (VAMP-3) (Cellubrevin) (CEB) (Synaptobrevin-3)
Gene: VAMP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	35271311, 32900848
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 236 Hs			1 100
+	Hs
		306781 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		VAMP5_HUMAN (11-80): 1.96e-20: 80.4: 38.57
+	Hs
		583878 CD53_HUMAN (1-234): 4.26e-47: 157: 29.06		VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00
+	Hs
		237795 TSN3_HUMAN (4-236): 1.19e-43: 149: 18.88		VAMP7_HUMAN (7-79): 4.38e-23: 90: 31.51
+	Hs
		306755 CD53_HUMAN (1-234): 4.26e-47: 157: 29.06		VAMP5_HUMAN (11-80): 1.96e-20: 80.4: 38.57