HitPredict

Interactor 1: CD81 (P60033)
CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the antiproliferative antibody 1) (Tetraspanin-28) (Tspan-28) (CD antigen CD81)
Gene: CD81

Interactor 2: TSN14 (Q8NG11)
Tetraspanin-14 (Tspan-14) (DC-TM4F2) (Transmembrane 4 superfamily member 14)
Gene: TSPAN14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	32900848
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Tetraspanin~Tetraspanin
Common GO terms	GO:0005886 - plasma membrane GO:0072659 - protein localization to plasma membrane GO:0097197 - tetraspanin-enriched microdomain
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 236 Hs			1 270
+	Hs
		887767 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		TSN5_HUMAN (1-268): 1.21e-84: 255: 57.84
+	Hs
		905534 TSN5_HUMAN (7-235): 3.13e-55: 179: 21.67		TSN14_HUMAN (1-270): 1.43e-85: 258: 100.00
+	Hs
		326050 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		TSN15_HUMAN (5-268): 2.25e-61: 197: 31.82
+	Hs
		653089 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		CD82_HUMAN (9-264): 3.26e-58: 188: 22.43
+	Hs
		209300 TSN6_HUMAN (1-234): 4.88e-57: 183: 22.13		TSN15_HUMAN (5-268): 2.25e-61: 197: 31.82
+	Hs
		326051 TSN5_HUMAN (7-235): 3.13e-55: 179: 21.67		TSN15_HUMAN (5-268): 2.25e-61: 197: 31.82
+	Hs
		326042 CD151_HUMAN (3-231): 1.89e-54: 176: 25.40		TSN15_HUMAN (5-268): 2.25e-61: 197: 31.82
+	Hs
		819444 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		CD151_HUMAN (7-262): 6.84e-53: 174: 23.94
+	Hs
		653088 CD151_HUMAN (3-231): 1.89e-54: 176: 25.40		CD82_HUMAN (9-264): 3.26e-58: 188: 22.43
+	Hs
		887757 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		CD81_HUMAN (6-264): 1.47e-50: 167: 22.10
+	Hs
		156137 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		TSN4_HUMAN (15-261): 2.13e-49: 164: 25.30
+	Hs
		602238 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		CD9_HUMAN (6-265): 3.09e-47: 158: 23.49
+	Hs
		279369 TSN5_HUMAN (7-235): 3.13e-55: 179: 21.67		TSN9_HUMAN (9-268): 3.58e-53: 174: 24.05
+	Hs
		819445 TSN5_HUMAN (7-235): 3.13e-55: 179: 21.67		CD151_HUMAN (7-262): 6.84e-53: 174: 23.94
+	Hs
		111521 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		K4DIA7_HUMAN (7-243): 6.81e-46: 155: 24.17
+	Hs
		583868 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		CD53_HUMAN (15-263): 2.62e-45: 153: 22.09
+	Hs
		602239 TSN5_HUMAN (7-235): 3.13e-55: 179: 21.67		CD9_HUMAN (6-265): 3.09e-47: 158: 23.49
+	Hs
		602230 CD151_HUMAN (3-231): 1.89e-54: 176: 25.40		CD9_HUMAN (6-265): 3.09e-47: 158: 23.49
+	Hs
		237719 CD151_HUMAN (3-231): 1.89e-54: 176: 25.40		TSN2_HUMAN (16-160): 5.49e-14: 70.9: 31.08