HitPredict

Interactor 1: PCBP1 (P60335)
Poly(rC)-binding protein 1 (Alpha-CP1) (Heterogeneous nuclear ribonucleoprotein E1) (hnRNP E1)
Gene: PCBP1

Interactor 2: IF2B2 (Q5SF07)
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (IGF-II mRNA-binding protein 2) (VICKZ family member 2)
Gene: Igf2bp2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	34133714
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	KH_1~KH_1
Common GO terms	GO:0003730 - mRNA 3'-UTR binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 356 Mm			1 592
+	Hs
		1072092 PCBP1_HUMAN (1-356): 2.47e-107: 320: 100.00		IF2B2_HUMAN (1-592): 7.77e-145: 433: 92.82
+	Hs
		1072219 PCBP2_HUMAN (1-352): 1.2e-97: 295: 81.44		IF2B2_HUMAN (1-592): 7.77e-145: 433: 92.82
+	Hs
		128188 PCBP1_HUMAN (1-356): 2.47e-107: 320: 100.00		IF2B3_HUMAN (2-592): 1.42e-132: 401: 62.06
+	Hs
		1072046 PCBP1_HUMAN (1-356): 2.47e-107: 320: 100.00		IF2B1_HUMAN (2-592): 5.99e-129: 392: 64.06
+	Hs
		1072196 PCBP2_HUMAN (1-352): 1.2e-97: 295: 81.44		IF2B1_HUMAN (2-592): 5.99e-129: 392: 64.06
+	Mm
		291665 HNRPK_MOUSE (7-353): 1.94e-68: 223: 22.51		IF2B1_MOUSE (2-592): 3.2e-129: 392: 63.73
+	Hs
		884308 PCBP1_HUMAN (1-356): 2.47e-107: 320: 100.00		PCBP3_HUMAN (252-577): 1.85e-27: 116: 16.81
+	Hs
		1071958 PCBP1_HUMAN (1-356): 2.47e-107: 320: 100.00		FUBP1_HUMAN (408-576): 1.32e-20: 97.9: 22.60
+	Hs
		884309 PCBP2_HUMAN (1-352): 1.2e-97: 295: 81.44		PCBP3_HUMAN (252-577): 1.85e-27: 116: 16.81
+	Mm
		888806 PCBP1_MOUSE (1-356): 2.47e-107: 320: 100.00		Q3TIX6_MOUSE (189-411): 3.16e-16: 84.1: 19.18
+	Hs
		884381 PCBP1_HUMAN (1-356): 2.47e-107: 320: 100.00		PCBP4_HUMAN (173-393): 3.04e-15: 80: 14.64
+	Mm
		888797 PCBP1_MOUSE (1-356): 2.47e-107: 320: 100.00		HNRPK_MOUSE (257-344): 1.49e-11: 68.8: 21.59
+	Hs
		903947 PCBP1_HUMAN (1-356): 2.47e-107: 320: 100.00		HNRPK_HUMAN (257-344): 1.49e-11: 68.8: 21.59
+	Hs
		1071869 PCBP1_HUMAN (1-356): 2.47e-107: 320: 100.00		PCBP1_HUMAN (491-586): 8.05e-11: 65.8: 16.67
+	Hs
		1071870 PCBP1_HUMAN (1-356): 2.47e-107: 320: 100.00		PCBP2_HUMAN (491-586): 1.73e-09: 61.9: 16.67
+	Hs
		903948 PCBP2_HUMAN (1-352): 1.2e-97: 295: 81.44		HNRPK_HUMAN (257-344): 1.49e-11: 68.8: 21.59
+	Hs
		1072094 PCBP2_HUMAN (1-352): 1.2e-97: 295: 81.44		PCBP2_HUMAN (491-586): 1.73e-09: 61.9: 16.67
+	Mm
		904265 PCBP2_MOUSE (1-352): 8.56e-95: 288: 79.28		HNRPK_MOUSE (257-344): 1.49e-11: 68.8: 21.59