HitPredict

Interactor 1: H11 (D4A3K5)
Histone H1.1 (Histone H1a)
Gene: H1-1

Interactor 2: Q6P751 (Q6P751)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2)
Gene: Cdk2

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.50	0.550

Property	Details
Experiments	9344597, 14985333
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 214 Rn			1 298
+	Rn
		413197 H1T_RAT (1-209): 2.82e-38: 133: 45.93		Q6P751_RAT (1-298): 3.38e-166: 464: 100.00
+	Hs
		559328 H13_HUMAN (1-182): 7.2e-25: 99: 51.65		CDK2_HUMAN (1-298): 1.46e-166: 465: 98.99
+	Hs
		558990 H15_HUMAN (1-117): 2.62e-20: 87.1: 67.80		CDK2_HUMAN (1-298): 1.46e-166: 465: 98.99
+	Hs
		625377 H11_HUMAN (40-145): 1.11e-16: 77.1: 76.15		CDK2_HUMAN (1-298): 1.46e-166: 465: 98.99
+	Mm
		794656 H15_MOUSE (17-197): 1.49e-21: 90.2: 55.85		CDK2_MOUSE (1-298): 1.59e-157: 444: 86.13
+	Mm
		794643 H11_MOUSE (1-124): 4.03e-19: 83.6: 92.74		CDK2_MOUSE (1-298): 1.59e-157: 444: 86.13
+	Mm
		550489 H12_MOUSE (34-117): 6.04e-17: 77.8: 82.14		CDK2_MOUSE (1-298): 1.59e-157: 444: 86.13
+	Hs
		414717 H13_HUMAN (1-182): 7.2e-25: 99: 51.65		CDK1_HUMAN (1-289): 2.57e-143: 406: 66.55
+	Rn
		88899 H11_RAT (1-181): 6.29e-25: 99: 100.00		CDK1_RAT (1-289): 2.77e-143: 406: 65.86
+	Hs
		414716 H15_HUMAN (1-117): 2.62e-20: 87.1: 67.80		CDK1_HUMAN (1-289): 2.57e-143: 406: 66.55
+	Mm
		509472 H11_MOUSE (1-124): 4.03e-19: 83.6: 92.74		CDK1_MOUSE (1-289): 2.76e-142: 404: 65.86
+	Hs
		559654 H12_HUMAN (1-175): 1.09e-22: 92.8: 52.57		CDK5_HUMAN (1-292): 1.73e-138: 394: 59.73
+	Hs
		489003 H14_HUMAN (1-148): 1.58e-21: 90.2: 58.11		CDK5_HUMAN (1-292): 1.73e-138: 394: 59.73
+	Hs
		414874 H11_HUMAN (40-145): 1.11e-16: 77.1: 76.15		CDK1_HUMAN (1-289): 2.57e-143: 406: 66.55
+	Mm
		509461 H12_MOUSE (34-117): 6.04e-17: 77.8: 82.14		CDK1_MOUSE (1-289): 2.76e-142: 404: 65.86
+	Hs
		559065 H15_HUMAN (1-117): 2.62e-20: 87.1: 67.80		CDK5_HUMAN (1-292): 1.73e-138: 394: 59.73
+	Mm
		794639 H11_MOUSE (1-124): 4.03e-19: 83.6: 92.74		CDK5_MOUSE (1-292): 2.01e-138: 394: 59.73
+	Hs
		559352 H13_HUMAN (1-182): 7.2e-25: 99: 51.65		CDK7_HUMAN (2-298): 2.14e-124: 360: 43.67
+	Hs
		559612 H12_HUMAN (1-175): 1.09e-22: 92.8: 52.57		CDK7_HUMAN (2-298): 2.14e-124: 360: 43.67
+	Hs
		488949 H14_HUMAN (1-148): 1.58e-21: 90.2: 58.11		CDK7_HUMAN (2-298): 2.14e-124: 360: 43.67