HitPredict

Interactor 1: KR105 (P60370)
Keratin-associated protein 10-5 (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5)
Gene: KRTAP10-5

Interactor 2: LCE3D (Q9BYE3)
Late cornified envelope protein 3D (Late envelope protein 16) (Small proline-rich-like epidermal differentiation complex protein 6A) (Small proline-rich-like epidermal differentiation complex protein 6B)
Gene: LCE3D

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 271 Hs			1 92
+	Hs
		889060 KR105_HUMAN (1-271): 4.64e-69: 216: 100.00		LCE3E_HUMAN (1-92): 5.34e-37: 121: 95.65
+	Hs
		888700 KR101_HUMAN (1-271): 1.89e-59: 191: 87.23		LCE3E_HUMAN (1-92): 5.34e-37: 121: 95.65
+	Hs
		888762 KR101_HUMAN (1-271): 1.89e-59: 191: 87.23		LCE3D_HUMAN (1-92): 4.43e-37: 121: 100.00
+	Hs
		889059 KR105_HUMAN (1-271): 4.64e-69: 216: 100.00		LCE3C_HUMAN (22-92): 1.38e-14: 64.7: 80.82
+	Hs
		889154 KR106_HUMAN (12-271): 5.43e-39: 141: 54.85		LCE3E_HUMAN (1-92): 5.34e-37: 121: 95.65
+	Hs
		889196 KR106_HUMAN (12-271): 5.43e-39: 141: 54.85		LCE3D_HUMAN (1-92): 4.43e-37: 121: 100.00
+	Hs
		889777 KR109_HUMAN (2-239): 2.7e-38: 137: 47.06		LCE3E_HUMAN (1-92): 5.34e-37: 121: 95.65
+	Hs
		889879 KR109_HUMAN (2-239): 2.7e-38: 137: 47.06		LCE3D_HUMAN (1-92): 4.43e-37: 121: 100.00
+	Hs
		888699 KR101_HUMAN (1-271): 1.89e-59: 191: 87.23		LCE3C_HUMAN (22-92): 1.38e-14: 64.7: 80.82
+	Hs
		889267 KR107_HUMAN (14-235): 2.14e-35: 131: 50.22		LCE3E_HUMAN (1-92): 5.34e-37: 121: 95.65
+	Hs
		889386 KR107_HUMAN (14-235): 2.14e-35: 131: 50.22		LCE3D_HUMAN (1-92): 4.43e-37: 121: 100.00
+	Hs
		889504 KR108_HUMAN (2-182): 4.7e-30: 115: 44.75		LCE3E_HUMAN (1-92): 5.34e-37: 121: 95.65
+	Hs
		889657 KR108_HUMAN (2-182): 4.7e-30: 115: 44.75		LCE3D_HUMAN (1-92): 4.43e-37: 121: 100.00
+	Hs
		889153 KR106_HUMAN (12-271): 5.43e-39: 141: 54.85		LCE3C_HUMAN (22-92): 1.38e-14: 64.7: 80.82
+	Hs
		889935 KR10B_HUMAN (2-235): 4.91e-39: 139: 48.54		LCE3C_HUMAN (22-92): 1.38e-14: 64.7: 80.82
+	Hs
		889776 KR109_HUMAN (2-239): 2.7e-38: 137: 47.06		LCE3C_HUMAN (22-92): 1.38e-14: 64.7: 80.82
+	Hs
		889266 KR107_HUMAN (14-235): 2.14e-35: 131: 50.22		LCE3C_HUMAN (22-92): 1.38e-14: 64.7: 80.82
+	Hs
		887732 KR10A_HUMAN (1-271): 8.32e-31: 117: 65.07		LCE3C_HUMAN (22-92): 1.38e-14: 64.7: 80.82
+	Hs
		889503 KR108_HUMAN (2-182): 4.7e-30: 115: 44.75		LCE3C_HUMAN (22-92): 1.38e-14: 64.7: 80.82
+	Hs
		888887 KR103_HUMAN (1-205): 2.8e-30: 114: 48.87		LCE3C_HUMAN (22-92): 1.38e-14: 64.7: 80.82