HitPredict

Interactor 1: KR108 (P60410)
Keratin-associated protein 10-8 (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8)
Gene: KRTAP10-8

Interactor 2: KRA44 (Q9BYR3)
Keratin-associated protein 4-4 (Keratin-associated protein 4-13) (Keratin-associated protein 4.13) (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.4)
Gene: KRTAP4-4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.615

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, mammalian protein protein interaction trap
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0045095 - keratin filament
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 259 Hs			1 166
+	Hs
		889642 KR108_HUMAN (1-259): 9.97e-60: 191: 100.00		KR412_HUMAN (1-166): 1.13e-30: 111: 63.18
+	Hs
		889570 KR108_HUMAN (1-259): 9.97e-60: 191: 100.00		KRA13_HUMAN (2-165): 1.33e-27: 102: 36.36
+	Hs
		887345 KR108_HUMAN (1-259): 9.97e-60: 191: 100.00		KR122_HUMAN (28-166): 1.43e-26: 99.4: 34.29
+	Hs
		889446 KR108_HUMAN (1-259): 9.97e-60: 191: 100.00		KR109_HUMAN (3-156): 1.49e-24: 97.9: 33.14
+	Hs
		889663 KR108_HUMAN (1-259): 9.97e-60: 191: 100.00		KR411_HUMAN (4-131): 1.38e-24: 95.9: 43.14
+	Hs
		888840 KR108_HUMAN (1-259): 9.97e-60: 191: 100.00		KR103_HUMAN (2-141): 2.41e-23: 93.2: 34.42
+	Hs
		889042 KR108_HUMAN (1-259): 9.97e-60: 191: 100.00		KR105_HUMAN (14-166): 1.68e-22: 92.1: 33.33
+	Hs
		889221 KR108_HUMAN (1-259): 9.97e-60: 191: 100.00		KR107_HUMAN (11-165): 6.43e-20: 86.7: 26.34
+	Hs
		889445 KR108_HUMAN (1-259): 9.97e-60: 191: 100.00		KR108_HUMAN (19-165): 2.65e-18: 80.9: 28.81
+	Hs
		889661 KR108_HUMAN (1-259): 9.97e-60: 191: 100.00		KRA93_HUMAN (2-151): 2.17e-17: 76.3: 37.42
+	Hs
		888681 KR108_HUMAN (1-259): 9.97e-60: 191: 100.00		KR101_HUMAN (32-166): 6.51e-15: 72: 30.22
+	Hs
		889447 KR108_HUMAN (1-259): 9.97e-60: 191: 100.00		KR10B_HUMAN (3-136): 3.54e-14: 70.1: 29.01
+	Hs
		889659 KR108_HUMAN (1-259): 9.97e-60: 191: 100.00		KRA98_HUMAN (2-126): 1.54e-13: 66.3: 35.20
+	Hs
		889660 KR108_HUMAN (1-259): 9.97e-60: 191: 100.00		KRA94_HUMAN (46-166): 1.08e-13: 66.3: 42.15
+	Hs
		887730 KR108_HUMAN (1-259): 9.97e-60: 191: 100.00		KR10A_HUMAN (19-136): 7.33e-12: 63.2: 34.17
+	Hs
		889662 KR108_HUMAN (1-259): 9.97e-60: 191: 100.00		KRA92_HUMAN (3-116): 3.48e-12: 62.8: 43.36
+	Hs
		889569 KR108_HUMAN (1-259): 9.97e-60: 191: 100.00		KR111_HUMAN (10-164): 1.45e-11: 60.9: 27.10
+	Hs
		889458 KR108_HUMAN (1-259): 9.97e-60: 191: 100.00		KRA11_HUMAN (2-106): 2.23e-10: 58.2: 30.19
+	Hs
		887301 KR108_HUMAN (1-259): 9.97e-60: 191: 100.00		KR121_HUMAN (51-137): 6.05e-10: 55.1: 31.03
+	Hs
		888525 KR108_HUMAN (1-259): 9.97e-60: 191: 100.00		KR123_HUMAN (34-126): 2.53e-09: 53.6: 31.18