Interactor 1: PTEN (P60484)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Inositol polyphosphate 3-phosphatase) (EC 3.1.3.-) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog)
Gene: PTEN

Interactor 2: NHRF2 (Q15599)
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (NHE3 kinase A regulatory protein E3KARP) (SRY-interacting protein 1) (SIP-1) (Sodium-hydrogen exchanger regulatory factor 2) (Solute carrier family 9 isoform A3 regulatory factor 2) (Tyrosine kinase activator protein 1) (TKA-1)
Gene: NHERF2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.59 0.60 0.596

The method score is based on:

Property Details
Experiments 16456542
Identification Methods pull down, affinity chromatography technology, filter binding, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005886 - plasma membrane
GO:0016324 - apical plasma membrane
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 403
Hs

1 337
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024