HitPredict

Interactor 1: PP4C (P60510)
Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (Pp4) (EC 3.1.3.16) (Protein phosphatase X) (PP-X)
Gene: PPP4C

Interactor 2: PP4R4 (Q6NUP7)
Serine/threonine-protein phosphatase 4 regulatory subunit 4
Gene: PPP4R4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.728

Property	Details
Experiments	28514442, 18715871, 27880917, 33961781, 19156129
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 307 Hs			1 873
+	Mm
		956531 PP4C_MOUSE (1-307): 0: 536: 100.00		PP4R4_MOUSE (1-873): 0: 988: 90.86
+	Hs
		672395 PP4C_HUMAN (1-307): 0: 536: 100.00		2AAB_HUMAN (71-676): 0: 595: 17.60
+	Hs
		87319 PP2AB_HUMAN (6-307): 0: 523: 65.23		C9J9C1_HUMAN (63-676): 0: 598: 16.35
+	Hs
		87320 PP2AA_HUMAN (6-307): 0: 522: 65.89		C9J9C1_HUMAN (63-676): 0: 598: 16.35
+	Hs
		672399 PP2AB_HUMAN (6-307): 0: 523: 65.23		2AAB_HUMAN (71-676): 0: 595: 17.60
+	Hs
		672402 PP2AA_HUMAN (6-307): 0: 522: 65.89		2AAB_HUMAN (71-676): 0: 595: 17.60
+	Dm
		619857 PP2A_DROME (2-307): 0: 522: 64.05		2AAA_DROME (63-667): 0: 549: 16.67
+	Hs
		268640 PP4C_HUMAN (1-307): 0: 536: 100.00		SF3B1_HUMAN (39-691): 5.27e-80: 284: 12.16
+	Hs
		268648 PP1A_HUMAN (2-304): 0: 517: 43.89		SF3B1_HUMAN (39-691): 5.27e-80: 284: 12.16
+	Bt
		61642 PP4C_BOVIN (1-307): 0: 536: 100.00		F1MRS1_BOVIN (213-461): 1.26e-15: 83.7: 12.94
+	Hs
		890987 PP4C_HUMAN (1-307): 0: 536: 100.00		PP4R1_HUMAN (95-493): 1.54e-11: 70.6: 11.81
+	Sp
		619320 PP2A2_SCHPO (2-307): 0: 507: 63.40		2AAA_SCHPO (243-680): 1.8e-18: 92.2: 11.14
+	Hs
		672060 PP4C_HUMAN (1-307): 0: 536: 100.00		2AAA_HUMAN (396-680): 4.73e-09: 62.1: 11.93
+	Hs
		915244 PP2AB_HUMAN (6-307): 0: 523: 65.23		PP4R1_HUMAN (95-493): 1.54e-11: 70.6: 11.81
+	Hs
		930933 PP2AA_HUMAN (6-307): 0: 522: 65.89		PP4R1_HUMAN (95-493): 1.54e-11: 70.6: 11.81
+	Hs
		672072 PP2AB_HUMAN (6-307): 0: 523: 65.23		2AAA_HUMAN (396-680): 4.73e-09: 62.1: 11.93
+	Mm
		915332 PP2AB_MOUSE (6-307): 0: 523: 65.23		2AAA_MOUSE (396-680): 4.53e-09: 62.1: 11.93
+	Hs
		672079 PP2AA_HUMAN (6-307): 0: 522: 65.89		2AAA_HUMAN (396-680): 4.73e-09: 62.1: 11.93
+	Mm
		930638 PP2AA_MOUSE (6-307): 0: 522: 65.89		2AAA_MOUSE (396-680): 4.53e-09: 62.1: 11.93
+	Sp
		619310 PP2A1_SCHPO (2-307): 3.56e-154: 435: 63.19		2AAA_SCHPO (243-680): 1.8e-18: 92.2: 11.14