HitPredict

Interactor 1: GBRL2 (P60520)
Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (General protein transport factor p16) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16) (MAP1 light chain 3-related protein)
Gene: GABARAPL2

Interactor 2: NBR1 (Q14596)
Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B)
Gene: NBR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.708

Property	Details
Experiments	20562859, 33545068, 19250911, 23022382
Identification Methods	affinity chromatography technology, proximity labelling technology, two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005776 - autophagosome GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 117 Hs			1 966
+	Hs
		306175 GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27		NBR1_HUMAN (1-966): 0: 1811: 100.00
+	Hs
		1056126 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		NBR1_HUMAN (1-966): 0: 1811: 100.00
+	Hs
		1056120 MLP3C_HUMAN (5-116): 5.09e-45: 144: 42.11		NBR1_HUMAN (1-966): 0: 1811: 100.00
+	Hs
		1056129 MLP3A_HUMAN (5-117): 2.01e-45: 144: 41.74		NBR1_HUMAN (1-966): 0: 1811: 100.00
+	Hs
		1056123 MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14		NBR1_HUMAN (1-966): 0: 1811: 100.00
+	Mm
		956458 MLP3A_MOUSE (5-117): 2.01e-45: 144: 41.74		NBR1_MOUSE (1-966): 0: 1731: 82.15
+	At
		1227908 ATG8A_ARATH (2-116): 2.67e-62: 187: 60.00		NBR1_ARATH (363-479): 3.2e-43: 170: 33.88
+	At
		1248233 ATG8C_ARATH (2-117): 3.19e-62: 186: 56.90		NBR1_ARATH (363-479): 3.2e-43: 170: 33.88
+	At
		1351949 ATG8D_ARATH (3-117): 3.37e-62: 186: 57.39		NBR1_ARATH (363-479): 3.2e-43: 170: 33.88
+	At
		1258022 ATG8F_ARATH (2-117): 1.18e-61: 185: 62.07		NBR1_ARATH (363-479): 3.2e-43: 170: 33.88
+	At
		1351950 ATG8B_ARATH (2-116): 6.65e-61: 183: 60.00		NBR1_ARATH (363-479): 3.2e-43: 170: 33.88
+	At
		1339372 ATG8I_ARATH (3-116): 1.24e-53: 165: 47.37		NBR1_ARATH (363-479): 3.2e-43: 170: 33.88