HitPredict

Interactor 1: GBRL2 (P60520)
Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (General protein transport factor p16) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16) (MAP1 light chain 3-related protein)
Gene: GABARAPL2

Interactor 2: ULK2 (Q8IYT8)
Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2)
Gene: ULK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.563

Property	Details
Experiments	23043107, 20562859
Identification Methods	unspecified method, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000045 - autophagosome assembly GO:0005737 - cytoplasm GO:0005776 - autophagosome GO:0005829 - cytosol GO:0006914 - autophagy
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 117 Hs			1 1036
+	Hs
		306230 GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27		ULK2_HUMAN (1-1036): 0: 889: 100.00
+	Hs
		1223631 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		ULK2_HUMAN (1-1036): 0: 889: 100.00
+	Hs
		1223630 MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14		ULK2_HUMAN (1-1036): 0: 889: 100.00
+	Hs
		262249 GBRL2_HUMAN (1-117): 1.08e-58: 178: 100.00		ULK1_HUMAN (2-1029): 0: 709: 49.02
+	Hs
		262209 GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27		ULK1_HUMAN (2-1029): 0: 709: 49.02
+	Hs
		262317 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		ULK1_HUMAN (2-1029): 0: 709: 49.02
+	Hs
		262314 MLP3C_HUMAN (5-116): 5.09e-45: 144: 42.11		ULK1_HUMAN (2-1029): 0: 709: 49.02
+	Hs
		262319 MLP3A_HUMAN (5-117): 2.01e-45: 144: 41.74		ULK1_HUMAN (2-1029): 0: 709: 49.02
+	Hs
		262316 MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14		ULK1_HUMAN (2-1029): 0: 709: 49.02
+	Hs
		891314 GBRL2_HUMAN (1-117): 1.08e-58: 178: 100.00		SIK2_HUMAN (9-833): 1.64e-130: 420: 20.16
+	Ce
		999349 LGG1_CAEEL (1-116): 2.15e-55: 170: 57.76		UNC51_CAEEL (450-1029): 1.5e-80: 282: 20.75
+	Dm
		1228782 Q9W2S2_DROME (1-117): 5.35e-58: 176: 57.27		Q8MQJ7_DROME (719-1029): 2.85e-73: 262: 27.35
+	Sc
		746018 ATG8_YEAST (1-116): 1.06e-58: 178: 56.03		ATG1_YEAST (9-365): 5.92e-46: 181: 31.58
+	Hs
		1326170 MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14		STK36_HUMAN (8-271): 1.84e-39: 161: 37.59