HitPredict

Interactor 1: GBRL2 (P60520)
Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (General protein transport factor p16) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16) (MAP1 light chain 3-related protein)
Gene: GABARAPL2

Interactor 2: WDFY3 (Q8IZQ1)
WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy)
Gene: WDFY3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.589

Property	Details
Experiments	24668264
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, isothermal titration calorimetry
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000421 - autophagosome membrane GO:0005737 - cytoplasm GO:0005776 - autophagosome GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 117 Hs			1 3526
+	Hs
		1152287 Q6IAW1_HUMAN (1-117): 7.55e-57: 173: 57.27		WDFY3_HUMAN (1-3526): 0: 4218: 100.00
+	Hs
		306231 GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27		WDFY3_HUMAN (1-3526): 0: 4218: 100.00
+	Hs
		1224700 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		WDFY3_HUMAN (1-3526): 0: 4218: 100.00
+	Hs
		1224697 MLP3C_HUMAN (5-116): 5.09e-45: 144: 42.11		WDFY3_HUMAN (1-3526): 0: 4218: 100.00
+	Hs
		1224703 MLP3A_HUMAN (5-117): 2.01e-45: 144: 41.74		WDFY3_HUMAN (1-3526): 0: 4218: 100.00
+	Mm
		1167198 MLP3A_MOUSE (5-117): 2.01e-45: 144: 41.74		WDFY3_MOUSE (1-3526): 0: 4181: 95.97
+	Dm
		1370863 Q9W2S2_DROME (1-117): 5.35e-58: 176: 57.27		Q9VML2_DROME (9-3517): 0: 3285: 46.36
+	Hs
		891255 GBRL2_HUMAN (1-117): 1.08e-58: 178: 100.00		FAN_HUMAN (2475-3286): 1.81e-176: 571: 25.26
+	Hs
		306258 GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27		FAN_HUMAN (2475-3286): 1.81e-176: 571: 25.26
+	Hs
		1268699 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		FAN_HUMAN (2475-3286): 1.81e-176: 571: 25.26
+	Hs
		1268697 MLP3C_HUMAN (5-116): 5.09e-45: 144: 42.11		FAN_HUMAN (2475-3286): 1.81e-176: 571: 25.26
+	Hs
		1268700 MLP3A_HUMAN (5-117): 2.01e-45: 144: 41.74		FAN_HUMAN (2475-3286): 1.81e-176: 571: 25.26
+	Hs
		891030 GBRL2_HUMAN (1-117): 1.08e-58: 178: 100.00		WDR5_HUMAN (2952-3290): 6.23e-71: 244: 15.32
+	Hs
		1122381 MLP3C_HUMAN (5-116): 5.09e-45: 144: 42.11		WDR81_HUMAN (2651-2991): 4.05e-71: 269: 27.73
+	Hs
		209414 GBRL2_HUMAN (1-117): 1.08e-58: 178: 100.00		PLRG1_HUMAN (2934-3299): 1.42e-38: 155: 13.66
+	Hs
		209368 GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27		PLRG1_HUMAN (2934-3299): 1.42e-38: 155: 13.66
+	At
		1248230 ATG8E_ARATH (2-116): 3.89e-59: 179: 59.13		FREE1_ARATH (3421-3525): 2.23e-31: 135: 30.56
+	Hs
		891348 GBRL2_HUMAN (1-117): 1.08e-58: 178: 100.00		ANFY1_HUMAN (3457-3510): 6e-10: 67.8: 46.30
+	Hs
		306344 GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27		ANFY1_HUMAN (3457-3510): 6e-10: 67.8: 46.30
+	Hs
		1328056 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		ANFY1_HUMAN (3457-3510): 6e-10: 67.8: 46.30