HitPredict

Interactor 1: GBRL2 (P60520)
Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (General protein transport factor p16) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16) (MAP1 light chain 3-related protein)
Gene: GABARAPL2

Interactor 2: RETR1 (Q9H6L5)
Reticulophagy regulator 1 (Reticulophagy receptor 1)
Gene: RETREG1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.658

Property	Details
Experiments	32296183, 26040720, unassigned1304
Identification Methods	two hybrid, pull down, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 117 Hs			1 497
+	Hs
		306320 GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		1328030 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Mm
		1257559 MLP3B_MOUSE (2-116): 2.53e-44: 141: 38.46		RETR1_MOUSE (1-497): 0: 767: 87.32
+	Hs
		1330625 MLP3A_HUMAN (5-117): 2.01e-45: 144: 41.74		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		1326146 MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		61903 MP3B2_HUMAN (2-117): 3.99e-43: 139: 37.29		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		891208 GBRL2_HUMAN (1-117): 1.08e-58: 178: 100.00		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		306223 GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		1202377 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		1202382 MLP3A_HUMAN (5-117): 2.01e-45: 144: 41.74		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		1202374 MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		306234 GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27		RETR2_HUMAN (77-472): 2.56e-164: 477: 28.57
+	Hs
		1240861 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		RETR2_HUMAN (77-472): 2.56e-164: 477: 28.57
+	Hs
		1240862 MLP3A_HUMAN (5-117): 2.01e-45: 144: 41.74		RETR2_HUMAN (77-472): 2.56e-164: 477: 28.57
+	Hs
		1240860 MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14		RETR2_HUMAN (77-472): 2.56e-164: 477: 28.57