HitPredict

Interactor 1: GBRL2 (P60520)
Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (General protein transport factor p16) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16) (MAP1 light chain 3-related protein)
Gene: GABARAPL2

Interactor 2: ATG4B (Q9Y4P1)
Cysteine protease ATG4B (EC 3.4.22.-) (AUT-like 1 cysteine endopeptidase) (Autophagy-related cysteine endopeptidase 1) (Autophagin-1) (Autophagy-related protein 4 homolog B) (HsAPG4B) (hAPG4B)
Gene: ATG4B

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 19549685, 33961781, 20562859, 17353931, 28287329, 16169070, 32296183, 21900206, 15187094, unassigned1304
Identification Methods enzymatic study, affinity chromatography technology, pull down, two hybrid, protease assay, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid and 1 others

more...
Interaction Type direct interaction, physical association, protein cleavage, cleavage reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ATG8~Peptidase_C54
Common GO terms GO:0000045 - autophagosome assembly
GO:0000421 - autophagosome membrane
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006914 - autophagy
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 117
Hs

1 393
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Last updated: 15 Jul 2024