HitPredict

Interactor 1: IL2 (P60568)
Interleukin-2 (IL-2) (T-cell growth factor) (TCGF) (Aldesleukin)
Gene: IL2

Interactor 2: REL (Q04864)
Proto-oncogene c-Rel
Gene: REL

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	7623820, 1508203
Identification Methods	electrophoretic mobility supershift assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 153 Hs			1 619
+	Mm
		381343 IL2_MOUSE (1-151): 6.75e-71: 212: 57.23		TF65_MOUSE (2-576): 1.99e-167: 490: 38.89
+	Hs
		891381 IL2_HUMAN (1-153): 1.29e-80: 236: 100.00		TF65_HUMAN (2-576): 4.74e-158: 466: 37.89
+	Hs
		891386 IL2_HUMAN (1-153): 1.29e-80: 236: 100.00		NFAC3_HUMAN (1-610): 1.34e-128: 406: 15.35
+	Hs
		891387 IL2_HUMAN (1-153): 1.29e-80: 236: 100.00		NFAC2_HUMAN (1-504): 1.26e-88: 296: 14.84
+	Hs
		317942 IL2_HUMAN (1-153): 1.29e-80: 236: 100.00		NFAC1_HUMAN (1-486): 1.55e-76: 264: 15.32
+	Mm
		381344 IL2_MOUSE (1-151): 6.75e-71: 212: 57.23		NFAC2_MOUSE (1-485): 8.52e-85: 286: 15.34