HitPredict

Interactor 1: UB2G2 (P60604)
Ubiquitin-conjugating enzyme E2 G2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G2) (Ubiquitin carrier protein G2) (Ubiquitin-protein ligase G2)
Gene: UBE2G2

Interactor 2: RN168 (Q8IYW5)
E3 ubiquitin-protein ligase RNF168 (hRNF168) (EC 2.3.2.27) (RING finger protein 168) (RING-type E3 ubiquitin transferase RNF168)
Gene: RNF168

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	19690564
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0005829 - cytosol GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 165 Hs			1 571
+	Hs
		849367 UB2D1_HUMAN (4-164): 3.3e-73: 217: 36.03		RN168_HUMAN (1-571): 6.89e-90: 289: 100.00
+	Hs
		919783 UB2D2_HUMAN (4-164): 5.65e-73: 217: 36.03		RN168_HUMAN (1-571): 6.89e-90: 289: 100.00
+	Hs
		895843 UB2D3_HUMAN (4-164): 1.16e-71: 213: 34.78		RN168_HUMAN (1-571): 6.89e-90: 289: 100.00
+	Hs
		829039 UBE2A_HUMAN (1-162): 1.72e-67: 203: 38.89		TITIN_HUMAN (66-460): 7.94e-10: 64.5: 9.05